Evidence map›Paper›PMID 28865430›Full record

Trial reportBMC psychiatry2017

Aerobic training for improved memory in patients with stress-related exhaustion: a randomized controlled trial.

Therese Eskilsson, Lisbeth Slunga Järvholm, Hanna Malmberg Gavelin, Anna Stigsdotter Neely, Carl-Johan Boraxbekk

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03073772 nacompletednot on this map

Effects on Cognitive Function, Estimated as a Global Brain Score, by Cognitive and Physical Fitness Training Added to a Multimodal Rehabilitation Program for Patients With Exhaustion Disorder

TypeinterventionalSponsorUmeå UniversityRan2010 to 2014Enrolled161ConditionsExhaustion, Syndrome, Burnout SyndromeArmsComputer-based cognitive training, Physical fitness training
NCT07407829 narecruitingnot on this mapstarted 2025, after this paper: background citation

Step by Step Back - A Feasibility Study of a CBT-Based Physical Activity Intervention for Stress-Related Exhaustion

TypeinterventionalSponsorThe Swedish School of Sport and Health SciencesRan2025 to 2026Enrolled20ConditionsExhaustion Disorder, Stress-Related DisordersArmsCBT/ACT-based psychologist-delivered physical activity program
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Therese EskilssonDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, SE- 901 87, Umeå, Sweden. therese.eskilsson@umu.se.ORCID 0000-0002-2402-562X
Lisbeth Slunga JärvholmDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.
Hanna Malmberg GavelinDepartment of Psychology, Umeå University, Umeå, Sweden.
Anna Stigsdotter NeelyDepartment of Social and Psychological Studies, Karlstad University, Karlstad, Sweden.
Carl-Johan BoraxbekkDanish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with stress-related exhaustion suffer from cognitive impairments, which often remain after psychological treatment or work place interventions. It is important to find effective treatments that can address this problem. Therefore, the aim of this study was to investigate the effects on cognitive performance and psychological variables of a 12-week aerobic training program performed at a moderate-vigorous intensity for patients with exhaustion disorder who participated in a multimodal rehabilitation program.

methodsIn this open-label, parallel, randomized and controlled trial, 88 patients diagnosed with exhaustion disorder participated in a 24-week multimodal rehabilitation program. After 12 weeks in the program the patients were randomized to either a 12-week aerobic training intervention or to a control group with no additional training. Primary outcome measure was cognitive function, and secondary outcome measures were psychological health variables and aerobic capacity.

resultsIn total, 51% patients in the aerobic training group and 78% patients in the control group completed the intervention period. The aerobic training group significantly improved in maximal oxygen uptake and episodic memory performance. No additional improvement in burnout, depression or anxiety was observed in the aerobic group compared with controls.

conclusionAerobic training at a moderate-vigorous intensity within a multimodal rehabilitation program for patients with exhaustion disorder facilitated episodic memory. A future challenge would be the clinical implementation of aerobic training and methods to increase feasibility in this patient group.

trial registrationClinicalTrials.gov: NCT03073772 . Retrospectively registered 21 February 2017.

Indexed as

AdultAnxietyCognitionDepressionExerciseExercise TherapyFemaleHumansMaleMemory, EpisodicMiddle AgedResearch DesignStress, PsychologicalTreatment OutcomeAnxietyBurnoutCognitionDepressionEpisodic memoryExercise

Identifiers

PMID28865430
PMCPMC5581420

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.