Evidence map›Paper›PMID 28865004›Full record

ReviewEuropean biophysics journal : EBJ2017

Gold nanoparticles with patterned surface monolayers for nanomedicine: current perspectives.

Paolo Pengo, Maria Şologan, Lucia Pasquato, Filomena Guida, Sabrina Pacor, Alessandro Tossi, Francesco Stellacci, Domenico Marson, Silvia Boccardo, Sabrina Pricl and 1 more

Abstract readReview
In one paragraph

Review in European biophysics journal : EBJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Molecular Dynamics Simulations of Different Nanoparticles at Substrates.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Janus Ligand-Tethered Nanoparticles at Liquid-Liquid Interfaces.The journal of physical chemistry. B · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Bioorthogonal Click of Colloidal Gold Nanoparticles to Antibodies In vivo.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Adsorption of Polymer-Tethered Particles on Solid Surfaces.The journal of physical chemistry. B · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paolo PengoDepartment of Chemical and Pharmaceutical Sciences, INSTM Trieste Research Unit, University of Trieste, 34127, Trieste, Italy.
Maria ŞologanDepartment of Chemical and Pharmaceutical Sciences, INSTM Trieste Research Unit, University of Trieste, 34127, Trieste, Italy.
Lucia PasquatoDepartment of Chemical and Pharmaceutical Sciences, INSTM Trieste Research Unit, University of Trieste, 34127, Trieste, Italy.
Filomena GuidaDepartment of Architecture and Engineering (DEA), University of Trieste, 34127, Trieste, Italy.
Sabrina PacorDepartment of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Alessandro TossiDepartment of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Francesco StellacciInstitute of Materials, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
Domenico MarsonMolecular Simulation Engineering Laboratory (MOSE), DEA and INSTM Research Unit MOSE-DEA, University of Trieste, 34127, Trieste, Italy.
Silvia BoccardoMolecular Simulation Engineering Laboratory (MOSE), DEA and INSTM Research Unit MOSE-DEA, University of Trieste, 34127, Trieste, Italy.
Sabrina PriclMolecular Simulation Engineering Laboratory (MOSE), DEA and INSTM Research Unit MOSE-DEA, University of Trieste, 34127, Trieste, Italy.
Paola PosoccoMolecular Simulation Engineering Laboratory (MOSE), DEA and INSTM Research Unit MOSE-DEA, University of Trieste, 34127, Trieste, Italy. paola.posocco@dia.units.it.ORCID http://orcid.org/0000-0001-8129-1572

Funding

Italian Ministry of University Research RBSI14PBC6
6 · The paper itself

Abstract

Molecular self-assembly is a topic attracting intense scientific interest. Various strategies have been developed for construction of molecular aggregates with rationally designed properties, geometries, and dimensions that promise to provide solutions to both theoretical and practical problems in areas such as drug delivery, medical diagnostics, and biosensors, to name but a few. In this respect, gold nanoparticles covered with self-assembled monolayers presenting nanoscale surface patterns-typically patched, striped or Janus-like domains-represent an emerging field. These systems are particularly intriguing for use in bio-nanotechnology applications, as presence of such monolayers with three-dimensional (3D) morphology provides nanoparticles with surface-dependent properties that, in turn, affect their biological behavior. Comprehensive understanding of the physicochemical interactions occurring at the interface between these versatile nanomaterials and biological systems is therefore crucial to fully exploit their potential. This review aims to explore the current state of development of such patterned, self-assembled monolayer-protected gold nanoparticles, through step-by-step analysis of their conceptual design, synthetic procedures, predicted and determined surface characteristics, interactions with and performance in biological environments, and experimental and computational methods currently employed for their investigation.

Indexed as

Metal NanoparticlesGoldNanomedicineSurface PropertiesGoldCellsMembrane penetrationMixed self-assembled monolayersMolecular modelingNano-bio interfacePatchy gold nanoparticles

Identifiers

PMID28865004
PMCPMC5693983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.