Evidence map›Paper›PMID 28864972›Full record

ReviewCurrent topics in behavioral neurosciences

Oxytocin Modulation of Neural Circuits.

Mariela Mitre, Jessica Minder, Egzona X Morina, Moses V Chao, Robert C Froemke

Abstract readReview
In one paragraph

Review in Current topics in behavioral neurosciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mariela MitreSkirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY, USA.
Jessica MinderSkirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY, USA.
Egzona X MorinaSkirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY, USA.
Moses V ChaoSkirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY, USA.
Robert C FroemkeSkirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY, USA. robert.froemke@med.nyu.edu.
New York University · US

Funding

U19 Supplement 2023-FroemkeU19NS107616 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RICHARD W TSIEN · 2018 to 2026
$36.4M
MEDICAL SCIENTIST TRAININGT32GM007308 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PHILIPS, MARK REID · 1985 to 2019
$23.2M
Training Systems and Integrative NeuroscienceT32MH019524 · NIMH · NEW YORK UNIVERSITY · PI KIORPES, LYNNE · 1992 to 2025
$5.2M
Targets of Oxytocin Receptor SignalingR01MH119136 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHAO, MOSES VICTOR · 2019 to 2023
$2.3M
NIGMS NIH HHS T32 GM007308NIMH NIH HHS R01 MH119136NIMH NIH HHS T32 MH019524NINDS NIH HHS U19 NS107616
6 · The paper itself

Abstract

Oxytocin is a hypothalamic neuropeptide first recognized as a regulator of parturition and lactation which has recently gained attention for its ability to modulate social behaviors. In this chapter, we review several aspects of the oxytocinergic system, focusing on evidence for release of oxytocin and its receptor distribution in the cortex as the foundation for important networks that control social behavior. We examine the developmental timeline of the cortical oxytocin system as demonstrated by RNA, autoradiographic binding, and protein immunohistochemical studies, and describe how that might shape brain development and behavior. Many recent studies have implicated oxytocin in cognitive processes such as processing of sensory stimuli, social recognition, social memory, and fear. We review these studies and discuss the function of oxytocin in the young and adult cortex as a neuromodulator of central synaptic transmission and mediator of plasticity.

Indexed as

AnimalsBehavior, AnimalBrainHumansNeural PathwaysNeuronal PlasticityNeuronsOxytocinReceptors, OxytocinSocial BehaviorOxytocinReceptors, OxytocinCortexInhibitionNeuromodulationOxytocinSynaptic plasticity

Identifiers

PMID28864972
PMCPMC5834368
OpenAlexW2752823183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.