Evidence map›Paper›PMID 28864893›Full record

ArticleDoklady. Biochemistry and biophysics2017

The metabolic changes in tumor-associated macrophages during cancer grow in mice with Ehrlich ascites carcinoma.

E V Inzhevatkin, A A Savchenko

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Features and applications of Ehrlich tumor model in cancer studies: a literature review.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

E V InzhevatkinFederal Research Center Krasnoyarsk Scientific Center of the Siberian Branch of the RAS, Akademgorodok 50, Krasnoyarsk, 660036, Russia. inscience@mail.ru.
A A SavchenkoResearch Institute for Medical Problems in the North Division of Federal Research Center "Krasnoyarsk Scientific Center of the Siberian Branch of the RAS", ul. Partizana Zheleznyaka 3 G, Krasnoyarsk, 660022, Russia.
Krasnoyarsk Scientific Center · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we investigated the activity of the key NAD(P)-dependent dehydrogenases associated with macrophage tumors in mice with Ehrlich ascites carcinoma. It was shown that cancer grow is associated with the development of conditions in macrophages leading to a decrease in the substrate flow intensity in the tricarboxylic acid cycle, deceleration of oxidative deamination of L-glutamate, NADP regeneration, and a decrease in the antioxidant defense efficiency. There results are consistent with our recent concept on the nonspecific metabolic reaction of cells to extreme exposures.

Indexed as

AnimalsCarcinoma, Ehrlich TumorCell ProliferationMacrophagesMaleMice

Identifiers

PMID28864893
OpenAlexW2753715913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.