Evidence map›Paper›PMID 28864543›Full record

ArticleThe EMBO journal2017

Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.

Kiran Bountra, Gregor Hagelueken, Hassanul G Choudhury, Valentina Corradi, Kamel El Omari, Armin Wagner, Indran Mathavan, Séverine Zirah, Weixiao Yuan Wahlgren, D Peter Tieleman and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
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  6. Bioprotective Strategies to ControlInternational journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex inAngewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 5 countries.

Kiran BountraDepartment of Life Sciences, Imperial College London, London, UK.
Gregor HageluekenInstitute for Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany.
Hassanul G ChoudhuryDepartment of Life Sciences, Imperial College London, London, UK.
Valentina CorradiCentre for Molecular Simulation and Department of Biological Sciences, University of Calgary, Calgary, AB, Canada.
Kamel El OmariRutherford Appleton Laboratory, Research Complex at Harwell, Oxfordshire, UK.
Armin WagnerRutherford Appleton Laboratory, Research Complex at Harwell, Oxfordshire, UK.
Indran MathavanDepartment of Life Sciences, Imperial College London, London, UK.
Séverine ZirahCommunication Molecules and Adaptation of Microorganisms Laboratory (MCAM, UMR 7245 CNRS-MNHN), Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Sorbonne Universités, Paris, France.
Weixiao Yuan WahlgrenDepartment of Life Sciences, Imperial College London, London, UK.
D Peter TielemanCentre for Molecular Simulation and Department of Biological Sciences, University of Calgary, Calgary, AB, Canada.
Olav SchiemannInstitute for Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany.
Sylvie RebuffatCommunication Molecules and Adaptation of Microorganisms Laboratory (MCAM, UMR 7245 CNRS-MNHN), Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Sorbonne Universités, Paris, France.
Konstantinos BeisDepartment of Life Sciences, Imperial College London, London, UK kbeis@imperial.ac.uk.ORCID 0000-0001-5727-4721
Rutherford Appleton Laboratory · GBCentre National de la Recherche Scientifique · FRUniversity of Bonn · DEUniversity of Calgary · CA

Funding

Biotechnology and Biological Sciences Research CouncilCIHR MOP‐62690Medical Research Council MR/N020103/1
6 · The paper itself

Abstract

Certain pathogenic bacteria produce and release toxic peptides to ensure either nutrient availability or evasion from the immune system. These peptides are also toxic to the producing bacteria that utilize dedicated ABC transporters to provide self-immunity. The ABC transporter McjD exports the antibacterial peptide MccJ25 in

Indexed as

ATP-Binding Cassette TransportersBacteriocinsCrystallography, X-RayEscherichia coliEscherichia coli ProteinsModels, MolecularMolecular Dynamics SimulationProtein ConformationProtein TransportATP-Binding Cassette TransportersBacteriocinsEscherichia coli ProteinsMcjD protein, E colimicrocinantibacterial peptide ABC transportermembrane proteinmolecular dynamicsPELDORtransporter structure

Identifiers

PMID28864543
PMCPMC5641919
OpenAlexW2751523357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.