Evidence map›Paper›PMID 28864445›Full record

ArticleGenes & development2017

Dissection of the molecular circuitry controlling virulence in

Bonnie J Cuthbert, Wilma Ross, Amy E Rohlfing, Simon L Dove, Richard L Gourse, Richard G Brennan, Maria A Schumacher

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. The DNA damage response ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. Control ofMicroorganisms · 2020
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Bonnie J CuthbertDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Wilma RossDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Amy E RohlfingDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Simon L DoveDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Richard L GourseDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Richard G BrennanDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Maria A SchumacherDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Duke University · USUniversity of Wisconsin–Madison · USBoston Children's Hospital · USHarvard University · US

Funding

Mechanism, Activation, and Control of rRNA TranscriptionR37GM037048 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GOURSE, RICHARD L. · 2007 to 2016
$6.6M
MEDCHANISM, ACTIVATION, &CONTROL OF RRNA TRANSCRIPTIONR01GM037048 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GOURSE, RICHARD L. · 1986 to 2020
$5.9M
Control of virulence gene expression in Francisella tularensisR01AI081693 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DOVE, SIMON L · 2010 to 2014
$2.1M
Complete atomic dissection of the B. subtilis nitrogen regulatory pathwayR01GM115547 · NIGMS · DUKE UNIVERSITY · PI SCHUMACHER, MARIA · 2015 to 2018
$1.2M
Control of virulence gene expression in Francisella tularensisR56AI081693 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DOVE, SIMON L · 2018 to 2018
$489k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI081693NIAID NIH HHS R56 AI081693NIGMS NIH HHS R01 GM037048NIGMS NIH HHS R01 GM115547NIGMS NIH HHS R37 GM037048
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adhesins, BacterialBioterrorismCells, CulturedCrystallographyDNA-Binding ProteinsDNA-Directed RNA PolymerasesFrancisella tularensisGene Expression Regulation, BacterialGenomic IslandsGuanosine TetraphosphateHumansMacrophagesProtein ConformationTranscription, GeneticTularemiaVirulenceAdhesins, BacterialDNA-Binding ProteinsDNA-Directed RNA PolymerasesGuanosine TetraphosphateSspA protein, bacteriabioterrorismFrancisella tularensisMglAPigRppGppSspAvirulence

Identifiers

PMID28864445
PMCPMC5630020
OpenAlexW2750727388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.