Evidence map›Paper›PMID 28864119›Full record

ArticlePsychiatry research2017

Value-based decision making under uncertainty in hoarding and obsessive- compulsive disorders.

Helen Pushkarskaya, David Tolin, Lital Ruderman, Daniel Henick, J MacLaren Kelly, Christopher Pittenger, Ifat Levy

Abstract read
In one paragraph

Article in Psychiatry research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Delay Discounting and Risk Tolerance in Obsessive Compulsive Disorder: Results From the Global OCD Study.Clinical psychological science : a journal of the Association for Psychological Science · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Risking Everything in Obsessive-Compulsive Disorder: An Analogue Decision-Making Study.Journal of psychopathology and behavioral assessment · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helen PushkarskayaSection of Comparative Medicine, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: helen.pushkarskaya@yale.edu.
David TolinDepartment of Psychology, Yale University, New Haven, CT 06510, USA; Anxiety Disorders Center, Institute of Living, Hartford Hospital, Hartford, CT 06114, USA.
Lital RudermanSection of Comparative Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Daniel HenickDepartment of Psychology, Yale University, New Haven, CT 06510, USA.
J MacLaren KellyDepartment of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA.
Christopher PittengerDepartment of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA; Department of Psychology, Yale University, New Haven, CT 06510, USA; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.
Ifat LevySection of Comparative Medicine, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neurobiology, Yale School of Medicine, New Haven, CT 06510, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Glutamate in OCD: a magnetic resonance spectroscopy study.R01MH095790 · NIMH · YALE UNIVERSITY · PI PITTENGER, CHRISTOPHER JOHN · 2012 to 2016
$1.8M
Cognitive Bases of Risk-taking Over the Lifespan: Psychophysics & Brain ImagingR01AG033406 · NIA · YALE UNIVERSITY · PI GLIMCHER, PAUL W, LEVY, IFAT · 2010 to 2014
$1.6M
Neural correlates of Uncertainty Intolerance in Obsessive Compulsive DisorderK01MH101326 · NIMH · YALE UNIVERSITY · PI PUSHKARSKAYA, HELEN · 2014 to 2017
$731k
NCATS NIH HHS UL1 TR001863NIA NIH HHS R01 AG033406NIMH NIH HHS K01 MH101326NIMH NIH HHS R01 MH095790
6 · The paper itself

Abstract

Difficulties in decision making are a core impairment in a range of disease states. For instance, both obsessive- compulsive disorder (OCD) and hoarding disorder (HD) are associated with indecisiveness, inefficient planning, and enhanced uncertainty intolerance, even in contexts unrelated to their core symptomology. We examined decision-making patterns in 19 individuals with OCD, 19 individuals with HD, 19 individuals with comorbid OCD and HD, and 57 individuals from the general population, using a well-validated choice task grounded in behavioral economic theory. Our results suggest that difficulties in decision making in individuals with OCD (with or without comorbid HD) are linked to reduced fidelity of value-based decision making (i.e. increase in inconsistent choices). In contrast, we find that performance of individuals with HD on our laboratory task is largely intact. Overall, these results support our hypothesis that decision-making impairments in OCD and HD, which can appear quite similar clinically, have importantly different underpinnings. Systematic investigation of different aspects of decision making, under varying conditions, may shed new light on commonalities between and distinctions among clinical syndromes.

Indexed as

Decision MakingUncertaintyAdultComorbidityFemaleHoardingHoarding DisorderHumansMaleMiddle AgedObsessive-Compulsive Disorder

Identifiers

PMID28864119
PMCPMC5741294

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.