Evidence map›Paper›PMID 28864077›Full record

ArticleThe Journal of investigative dermatology2018

Phenotype and Antimicrobial Activity of Th17 Cells Induced by Propionibacterium acnes Strains Associated with Healthy and Acne Skin.

George W Agak, Stephanie Kao, Kelsey Ouyang, Min Qin, David Moon, Ahsan Butt, Jenny Kim

Open access · greenAbstract read
In one paragraph

Article in The Journal of investigative dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Acne and the cutaneous microbiome: A systematic review of mechanisms and implications for treatments.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Materials today. Bio · 2026
    Article
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  9. Review
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  15. Article
  16. Article
  17. A microRNA focus on acne.Dermatology reports · 2024
    Article
  18. Article
  19. Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

George W AgakDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. Electronic address: Gagak@mednet.ucla.edu.
Stephanie KaoDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Kelsey OuyangDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Min QinDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
David MoonDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Ahsan ButtDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Jenny KimDivision of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; California NanoSystems Institute, University of California, Los Angeles, California, USA.
University of California, Los Angeles · USCalifornia NanoSystems Institute · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZACK, JEROME A. · 1991 to 2018
$39.9M
Innate Immunity in Acne VulgarisR01AR053542 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KIM, JENNY J · 2009 to 2013
$1.3M
The nature of Propionibacterium acnes-induced inflammatory immune responses in acne vulgarisK01AR071479 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGAK, GEORGE W · 2017 to 2022
$958k
NCI NIH HHS P30 CA016042NIAID NIH HHS P30 AI028697NIAMS NIH HHS K01 AR071479NIAMS NIH HHS R01 AR053542
6 · The paper itself

Abstract

Studies of the human skin microbiome suggest that Propionibacterium acnes strains may contribute differently to skin health and disease. However, the immune phenotype and functions of T helper type 17 (Th17) cells induced by healthy (P

Indexed as

Acne VulgarisGram-Positive Bacterial InfectionsHumansInterleukinsLeukocytes, MononuclearLimulus TestMicrobial Sensitivity TestsMicrobiotaPropionibacterium acnesRecombinant ProteinsSkinTh17 CellsIL26 protein, humanInterleukinsRecombinant Proteins

Identifiers

PMID28864077
PMCPMC5794628
OpenAlexW2753833326

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.