Evidence map›Paper›PMID 28863144›Full record

ArticlePloS one2017

Latency modulation of collicular neurons induced by electric stimulation of the auditory cortex in Hipposideros pratti: In vivo intracellular recording.

Kang Peng, Yu-Jie Peng, Jing Wang, Ming-Jian Yang, Zi-Ying Fu, Jia Tang, Qi-Cai Chen

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kang PengSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Yu-Jie PengSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Jing WangSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Ming-Jian YangSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Zi-Ying FuSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Jia TangSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.
Qi-Cai ChenSchool of Life Sciences and Hubei Key Lab of Genetic Regulation & Integrative Biology, Central China Normal University, Wuhan, China.ORCID http://orcid.org/0000-0002-5093-2266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the auditory pathway, the inferior colliculus (IC) receives and integrates excitatory and inhibitory inputs from the lower auditory nuclei, contralateral IC, and auditory cortex (AC), and then uploads these inputs to the thalamus and cortex. Meanwhile, the AC modulates the sound signal processing of IC neurons, including their latency (i.e., first-spike latency). Excitatory and inhibitory corticofugal projections to the IC may shorten and prolong the latency of IC neurons, respectively. However, the synaptic mechanisms underlying the corticofugal latency modulation of IC neurons remain unclear. Thus, this study probed these mechanisms via in vivo intracellular recording and acoustic and focal electric stimulation. The AC latency modulation of IC neurons is possibly mediated by pre-spike depolarization duration, pre-spike hyperpolarization duration, and spike onset time. This study suggests an effective strategy for the timing sequence determination of auditory information uploaded to the thalamus and cortex.

Indexed as

Electric StimulationAcousticsAcoustic StimulationAnimalsAuditory CortexAuditory PathwaysAuditory PerceptionBody WeightCerebral CortexChiropteraEcholocationFemaleInferior ColliculiMaleNeuronsSound

Identifiers

PMID28863144
PMCPMC5580910

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.