Evidence map›Paper›PMID 28862950›Full record

Trial reportJournal of the American Heart Association2017

Cardiac Adaptations to High-Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study.

Jon Egelund, Peter G Jørgensen, Camilla M Mandrup, Thomas Fritz-Hansen, Bente Stallknecht, Jens Bangsbo, Michael Nyberg, Ylva Hellsten

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02135575 (Effects of Exercise Training on Cardiovascular Health in Middle-aged Women), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02135575 nacompletednot on this map

Effects of Exercise Training on Cardiovascular Health in Middle-aged Women

TypeinterventionalSponsorUniversity of CopenhagenRan2014 to 2017Enrolled36ConditionsMenopause, Cardiac Function Impaired, Cardiovascular Diseases, Blood Platelet DisordersArmsSpinning
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jon EgelundDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Peter G JørgensenDepartment of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark.
Camilla M MandrupDepartment of Biomedical Sciences, University of Copenhagen, Denmark.
Thomas Fritz-HansenDepartment of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark.
Bente StallknechtDepartment of Biomedical Sciences, University of Copenhagen, Denmark.
Jens BangsboDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Michael NybergDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
Ylva HellstenDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Denmark yhellsten@nexs.ku.dk.
University of Copenhagen · DKGentofte Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined the role of menopause on cardiac dimensions and function and assessed the efficacy of exercise training before and after menopause. METHODS AND

resultsTwo groups of healthy premenopausal (n=36, 49.4±0.3 years) and postmenopausal (n=37, 53.5±0.5 years) women with no history of cardiovascular disease and with a mean age difference between groups of only 4 years were studied. Cardiac dimensions and systolic and diastolic function were determined by transthoracic echocardiography with tissue Doppler imaging and 2-dimensional speckle tracking. Measurements were performed at baseline and after a 12-week period of high-intensity aerobic cycle training. LV internal diastolic diameter and LV mass were similar in the 2 groups at baseline and increased by ≈2% to 8% (

conclusionsThese results suggest that training-induced cardiac adaptations are preserved in the early postmenopausal phase. Furthermore, the hormonal changes associated with the menopausal transition do not appear to affect cardiac dimensions and function. CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT02135575.

Indexed as

ExercisePostmenopausePremenopauseAdaptation, PhysiologicalAtrial Function, LeftBicyclingDenmarkDiastoleEchocardiography, DopplerExercise TherapyFemaleHealth StatusHeartHeart RateHumansMiddle AgedE/A ratioexercise trainingmenopausetransthoracic echocardiographywomen

Identifiers

PMID28862950
PMCPMC5586415
OpenAlexW2747045512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.