Evidence map›Paper›PMID 28862937›Full record

Observational studyJournal of the American Heart Association2017

Predictors of Intramyocardial Hemorrhage After Reperfused ST-Segment Elevation Myocardial Infarction.

Raquel P Amier, Ruben Y G Tijssen, Paul F A Teunissen, Rodrigo Fernández-Jiménez, Gonzalo Pizarro, Inés García-Lunar, Teresa Bastante, Peter M van de Ven, Aernout M Beek, Martijn W Smulders and 4 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04789564 (Predictors of Cardiovascular Magnetic Resonancerelated Parameters), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04789564 completednot on this map

Predictors of Cardiovascular Magnetic Resonancerelated Parameters: Intramyocardial Hemorrhage, Microvascular Obstruction , Area at Risk and Strain Related Parameters, and Their Effects on Adverse Ventricular Remodeling and MACEs in STEMI Patients After Primary PCI

Typeobservational_patient_registrySponsorQian gengRan2014 to 2021Enrolled500ConditionsCardiovascular DiseasesArmscardiovascular magnetic resonance (CMR)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Raquel P AmierDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Ruben Y G TijssenDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Paul F A TeunissenDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Rodrigo Fernández-JiménezCentro Nacional Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Gonzalo PizarroCentro Nacional Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Inés García-LunarCentro Nacional Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Teresa BastanteDepartment of Cardiology, Hospital Universitario de La Princesa, Madrid, Spain.
Peter M van de VenDepartment of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.
Aernout M BeekDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Martijn W SmuldersDepartment of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Sebastiaan C A M BekkersDepartment of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands.
Niels van RoyenDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Borja IbanezCentro Nacional Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Robin NijveldtDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands robin@nijveldt.net.
Amsterdam UMC Location VUmc · NLSpanish National Centre for Cardiovascular Research · ESMaastricht University · NLCentro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital Universitario de La Princesa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFindings from recent studies show that microvascular injury consists of microvascular destruction and intramyocardial hemorrhage (IMH). Patients with ST-segment elevation myocardial infarction (STEMI) with IMH show poorer prognoses than patients without IMH. Knowledge on predictors for the occurrence of IMH after STEMI is lacking. The current study aimed to investigate the prevalence and extent of IMH in patients with STEMI and its relation with periprocedural and clinical variables. METHODS AND

resultsA multicenter observational cohort study was performed in patients with successfully reperfused STEMI with cardiovascular magnetic resonance examination 5.5±1.8 days after percutaneous coronary intervention. Microvascular injury was visualized using late gadolinium enhancement and T2-weighted cardiovascular magnetic resonance imaging for microvascular obstruction and IMH, respectively. The median was used as the cutoff value to divide the study population with presence of IMH into mild or extensive IMH. Clinical and periprocedural parameters were studied in relation to occurrence of IMH and extensive IMH, respectively. Of the 410 patients, 54% had IMH. The presence of IMH was independently associated with anterior infarction (odds ratio, 2.96; 95% CI, 1.73-5.06 [

conclusionsOccurrence of IMH was associated with anterior infarction and glycoprotein IIb/IIIa inhibitor treatment. Extensive IMH was associated with anterior infarction. IMH was associated with more severe infarction and worse short-term left ventricular function in patients with STEMI.

Indexed as

AgedAnterior Wall Myocardial InfarctionContrast MediaDatabases, FactualFemaleGadolinium DTPAHemorrhageHumansLogistic ModelsMagnetic Resonance Imaging, CineMaleMiddle AgedMultivariate AnalysisOdds RatioPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsContrast MediaGadolinium DTPAPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa Complexacute myocardial infarctioncardiac magnetic resonanceintramyocardial hemorrhagepercutaneous coronary interventionST‐segment elevation myocardial infarction

Identifiers

PMID28862937
PMCPMC5586425
OpenAlexW2746779649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.