ArticleMolecules (Basel, Switzerland)2017
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
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Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
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Who cites it
22 citing papers in PubMed, 87 citations in OpenAlex.
- Development of Isoniazid-Pyrazole Hybrids as Potential Antitubercular Agents.International journal of molecular sciences · 2026Article
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- Targeting InhA for Tuberculosis Therapy: A Review of Recent Advances in Enzyme Inhibition and Drug Development.Current drug targets · 2026Review
- Comprehensive biological evaluation of infuzide as a potent antimicrobial, alone and in combination with gentamicin, linezolid, and minocycline targeting MDRMicrobiology spectrum · 2025Article
- Synthesis, Structural Properties and Biological Activities of Novel Hydrazones of 2-, 3-, 4-Iodobenzoic Acid.Molecules (Basel, Switzerland) · 2024Article
- Exploring the synthesis, characterization, and corrosion inhibition of new tris-thiosemicarbazone derivatives for acidic steel settings using computational and experimental studies.Scientific reports · 2024Article
- Design, Synthesis, In Silico Studies and In Vitro Evaluation of New Indole- and/or Donepezil-like Hybrids as Multitarget-Directed Agents for Alzheimer's Disease.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Mechanochemical Studies on Coupling of Hydrazines and Hydrazine Amides with Phenolic and Furanyl Aldehydes-Hydrazones with Antileishmanial and Antibacterial Activities.Molecules (Basel, Switzerland) · 2023Article
- Synthesis, Molecular Docking Study, and Biological Evaluation of New 4-(2,5-Dimethyl-1Antibiotics (Basel, Switzerland) · 2023Article
- Recent Advances in Anti-Tuberculosis Drug Discovery Based on Hydrazide-Hydrazone and Thiadiazole Derivatives Targeting InhA.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Fungal Secondary Metabolites/Dicationic Pyridinium Iodide Combinations in Combat against Multi-Drug Resistant Microorganisms.Molecules (Basel, Switzerland) · 2023Article
- Article
- Reshuffle Bonds by Ball Milling: A Mechanochemical Protocol for Charge-Accelerated Aza-Claisen Rearrangements.Molecules (Basel, Switzerland) · 2023Article
- Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Biological and Biochemical Evaluation of Isatin-Isoniazid Hybrids as Bactericidal Candidates againstAntimicrobial agents and chemotherapy · 2021Article
- Novel Isoniazid-Carborane Hybrids Active in Vitro AgainstPharmaceuticals (Basel, Switzerland) · 2020Article
- Sustainable Synthesis of a Potent and Selective 5-HTThe Journal of organic chemistry · 2020Article
- In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors.Molecules (Basel, Switzerland) · 2020Article
- Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity AgainstFrontiers in cellular and infection microbiology · 2020Article
- Design, Synthesis, and Evaluation of Monoamine Oxidase A Inhibitors⁻Indocyanine Dyes Conjugates as Targeted Antitumor Agents.Molecules (Basel, Switzerland) · 2019Article
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Authors and funding
15 authors at 3 institutions in 3 countries.
Paulo F M OliveiraDepartment of Process Engineering, Université de Toulouse, Mines-Albi, CNRS UMR 5302, Centre RAPSODEE, Campus Jarlard, 81013 Albi, France. paul_marqs@hotmail.com.
Brigitte GuidettiDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. guidetti@chimie.ups-tlse.fr.
Alain ChamayouDepartment of Process Engineering, Université de Toulouse, Mines-Albi, CNRS UMR 5302, Centre RAPSODEE, Campus Jarlard, 81013 Albi, France. alain.chamayou@mines-albi.fr.
Christiane André-BarrèsDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. candre@chimie.ups-tlse.fr.
Jan MadackiDepartment of Biochemistry, Comenius University in Bratislava, Faculty of Natural Sciences, Mlynská Dolina, Ilkovičova 6, 84215 Bratislava, Slovakia. jan.madacki@gmail.com.
Jana KordulákováDepartment of Biochemistry, Comenius University in Bratislava, Faculty of Natural Sciences, Mlynská Dolina, Ilkovičova 6, 84215 Bratislava, Slovakia. kordulakova@fns.uniba.sk.
Giorgia MoriDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia; via Ferrata 1, 27100 Pavia, Italy. giorgia.mori@unipv.it.
Beatrice Silvia OrenaDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia; via Ferrata 1, 27100 Pavia, Italy. beatricesilvia.orena01@universitadipavia.it.
Laurent Roberto ChiarelliDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia; via Ferrata 1, 27100 Pavia, Italy. laurent.chiarelli@unipv.it.
Maria Rosalia PascaDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia; via Ferrata 1, 27100 Pavia, Italy. mariarosalia.pasca@unipv.it.
Christian LherbetDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. christian.lherbet@itav.fr.
Chantal CarayonDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. andre@chimie.ups-tlse.fr.
Stéphane MassouDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. massou@chimie.ups-tlse.fr.
Michel BaronDepartment of Process Engineering, Université de Toulouse, Mines-Albi, CNRS UMR 5302, Centre RAPSODEE, Campus Jarlard, 81013 Albi, France. baron@mines-albi.fr.
Michel BaltasDepartment of Chemistry, Université de Toulouse, UPS, CNRS UMR 5068, LSPCMIB, 118 Route de Narbonne, 31062 Toulouse, France. baltas@chimie.ups-tlse.fr.
Centre National de la Recherche Scientifique · FRUniversity of Pavia · ITComenius University Bratislava · SK
Funding
No grant is acknowledged in the PubMed record.
Abstract
A series of isoniazid derivatives bearing a phenolic or heteroaromatic coupled frame were obtained by mechanochemical means. Their pH stability and their structural (conformer/isomer) analysis were checked. The activity of prepared derivatives against
Indexed as
Antitubercular AgentsCell DeathCell LineChromatography, Thin LayerHumansHydrazonesHydrogen-Ion ConcentrationHydrolysisIsomerismIsoniazidMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsModels, MolecularMolecular ConformationMycobacterium tuberculosisQuantum TheoryAntitubercular AgentsHydrazonesIsoniazidhydrazonemechanochemistryMycobacterium tuberculosis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.