Evidence map›Paper›PMID 28862328›Full record

ArticleThe Journal of physiology2017

An allosteric gating model recapitulates the biophysical properties of I

Paolo Spaiardi, Elisa Tavazzani, Marco Manca, Veronica Milesi, Giancarlo Russo, Ivo Prigioni, Walter Marcotti, Jacopo Magistretti, Sergio Masetto

Open access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The potassium channel subunit KbioRxiv : the preprint server for biology · 2024
    Article
  6. Nonquantal transmission at the vestibular hair cell-calyx synapse: KProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Signal transmission in mature mammalian vestibular hair cells.Frontiers in cellular neuroscience · 2022
    Article
  8. Current Response in CaFrontiers in neuroscience · 2021
    Article
  9. Article
  10. KNeuroscience · 2020
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Paolo SpaiardiDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.
Elisa TavazzaniDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.
Marco MancaDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.
Veronica MilesiInstituto de Estudios Inmunológios y Fisiopatológicos (IIFP) - CONICET, Universidad Nacional de La Plata, La Plata, 1900, Argentina.
Giancarlo RussoDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.
Ivo PrigioniDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.
Walter MarcottiDepartment of Biomedical Science, University of Sheffield, Sheffield, S10 2TN, UK.ORCID 0000-0002-8770-7628
Jacopo MagistrettiDepartment of Biology and Biotechnology, University of Pavia, Pavia, 27100, Italy.
Sergio MasettoDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, 27100, Italy.ORCID 0000-0003-2955-8430
University of Pavia · ITConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Sheffield · GB

Funding

Wellcome Trust 102892Wellcome Trust 102892/Z/13/Z
6 · The paper itself

Abstract

key pointsVestibular type I and type II hair cells and their afferent fibres send information to the brain regarding the position and movement of the head. The characteristic feature of type I hair cells is the expression of a low-voltage-activated outward rectifying K ABSTRACT: Type I and type II hair cells are the sensory receptors of the mammalian vestibular epithelia. Type I hair cells are characterized by their basolateral membrane being enveloped in a single large afferent nerve terminal, named the calyx, and by the expression of a low-voltage-activated outward rectifying K

Indexed as

Ion Channel GatingAction PotentialsAllosteric RegulationAnimalsCells, CulturedFemaleHair Cells, VestibularMaleMicePotassium Channels, Voltage-GatedPotassium Channels, Voltage-Gatedchannel gating modelIK,Ltype I vestibular hair cell

Identifiers

PMID28862328
PMCPMC5663832
OpenAlexW2752798063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.