ArticleJournal of biomedical optics2017
Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026Review
- Multimodal optical imaging for the assessment of the teratogenic effects of ethanol on zebrafish development.Journal of biomedical optics · 2026Article
- Imaging the mechanical properties of a developing embryonic tendon using Brillouin microscopy.Acta biomaterialia · 2025Article
- Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation.Nature communications · 2025Article
- Measuring and manipulating mechanical forces during development.Nature cell biology · 2025Review
- Non-Invasive Measurement of Elasticity in Glioblastoma Multiforme Validates Decreased TMZ Sensitivity in Astrocyte Co-Culture.IEEE open journal of engineering in medicine and biology · 2025Article
- Harnessing quantum light for microscopic biomechanical imaging of cells and tissues.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Label-free, high-throughput holographic imaging to evaluate mammalian gametes and embryos†.Biology of reproduction · 2024Review
- Optical coherence tomography-guided Brillouin microscopy highlights regional tissue stiffness differences during anterior neural tube closure in the Mthfd1l murine mutant.Development (Cambridge, England) · 2024Article
- In vivo measurement of the biomechanical properties of human skin with motion-corrected Brillouin microscopy.Biomedical optics express · 2024Article
- Brillouin microscopy.Nature reviews. Methods primers · 2024Article
- Time-lapse mechanical imaging of neural tube closure in live embryo using Brillouin microscopy.Scientific reports · 2023Article
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
- Article
- Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo.Biology open · 2022Article
- Review
- Following the Beat: Imaging the Valveless Pumping Function in the Early Embryonic Heart.Journal of cardiovascular development and disease · 2022Review
- Foregut organ progenitors and their niche display distinct viscoelastic properties in vivo during early morphogenesis stages.Communications biology · 2022Article
- Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging.Optics letters · 2022Article
- Non-contact elastography methods in mechanobiology: a point of view.European biophysics journal : EBJ · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Embryogenesis is regulated by numerous changes in mechanical properties of the cellular microenvironment. Thus, studying embryonic mechanophysiology can provide a more thorough perspective of embryonic development, potentially improving early detection of congenital abnormalities as well as evaluating and developing therapeutic interventions. A number of methods and techniques have been used to study cellular biomechanical properties during embryogenesis. While some of these techniques are invasive or involve the use of external agents, others are compromised in terms of spatial and temporal resolutions. We propose the use of Brillouin microscopy in combination with optical coherence tomography (OCT) to measure stiffness as well as structural changes in a developing embryo. While Brillouin microscopy assesses the changes in stiffness among different organs of the embryo, OCT provides the necessary structural guidance.
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Registered trials
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