Evidence map›Paper›PMID 28861766›Full record

ArticleProbiotics and antimicrobial proteins2018

In Vitro Probiotic Properties of Lactobacillus salivarius MG242 Isolated from Human Vagina.

Chang-Ho Kang, Seul Hwa Han, YongGyeong Kim, Nam-Soo Paek, Jae-Seong So

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
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  4. UnderstandingFoods (Basel, Switzerland) · 2024
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  7. A Novel Strain of ProbioticMicroorganisms · 2023
    Article
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  9. Biocontrol ofAntibiotics (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Vulvovaginal candidiasis and current perspectives: new risk factors and laboratory diagnosis by using MALDI TOF for identifying species in primary infection and recurrence.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  16. Article
  17. Impact of HPV infection on vaginal microecology and maternal and neonatal outcomes.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chang-Ho KangDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, South Korea. changho-kang@naver.com.
Seul Hwa HanMEDIOGEN, Co., Ltd., Seoul, 04157, South Korea.
YongGyeong KimMEDIOGEN, Co., Ltd., Seoul, 04157, South Korea.
Nam-Soo PaekMEDIOGEN, Co., Ltd., Seoul, 04157, South Korea.
Jae-Seong SoDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, South Korea.
Insilicogen (South Korea) · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulvovaginal candidiasis (VVC) is a very common infection worldwide that is mainly caused by Candida albicans. In a previous study, we showed that Lactobacillus salivarius MG242 has anti-Gardnerella vaginalis activity. In this study, we investigated the potential of using L. salivarius MG242 for biocontrol of C. albicans. In line with the results from a spot overlay assay, MG242 inhibited the growth of C. albicans by 99.99 ± 0.01% in co-culture, suggesting that L. salivarius MG242 has the potential to be developed into a probiotic formula to treat or prevent VVC. Accelerated storage tests using dehydrated live cell powder at 50, 60, and 70 °C were performed, and the results showed that immobilization with 10% skim milk effectively increased the thermal resistance of entrapped microorganisms, resulting in sevenfold longer shelf-life than the control (in PBS). Lower storage temperatures also increased the shelf-life up to 8.31 months.

Indexed as

AntibiosisCandida albicansCandidiasis, VulvovaginalFemaleHumansLigilactobacillus salivariusProbioticsVaginaAccelerated storage testCandida albicansLactobacillus salivarius MG242

Identifiers

PMID28861766
OpenAlexW2753748632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.