Evidence map›Paper›PMID 28861732›Full record

ArticleJournal of autism and developmental disorders2017

Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood.

Alexander J Hinnebusch, Lauren E Miller, Deborah A Fein

Abstract readEvaluation Study
In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Overall prognosis of preschool autism spectrum disorder diagnoses.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Autism severity and its relationship to disability.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. The Toddler Autism Symptom Inventory: Use in diagnostic evaluations of toddlers.Autism : the international journal of research and practice · 2021
    Article
  14. Article
  15. Characteristics of toddlers with early versus later diagnosis of autism spectrum disorder.Autism : the international journal of research and practice · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Diagnosing Autism Spectrum Disorder in Children with Low Mental Age.Journal of autism and developmental disorders · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander J HinnebuschDepartment of Physical Medicine and Rehabilitation, University of Michigan Health System, 325 East Eisenhower Parkway, Suite 100, Ann Arbor, MI, 48108, USA.
Lauren E MillerDepartment of Psychological Sciences, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA. lauren.miller@uconn.edu.
Deborah A FeinDepartment of Psychological Sciences, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.

Funding

Early Detection of Pervasive Developmental DisordersR01HD039961 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI ROBINS, DIANA L · 2002 to 2018
$11.5M
NICHD NIH HHS R01 HD039961
6 · The paper itself

Abstract

Some children with autism spectrum disorders (ASDs) exhibit low mental age (Low-MA; i.e., cognitive functioning below 12 months). We examined diagnosis, symptom severity, and development in children with ASD-low MA (n = 25), autistic disorder (n = 111), and PDD-NOS (n = 82) at ages two and four. We predicted that some ASD-low MA children would demonstrate just intellectual impairment and not autism symptoms on follow-up, with social deficits at age two attributable to global delays. Instead, most ASD-low MA children (96%) had an ASD at follow-up, compared to children initially diagnosed with autistic disorder (86.5%) or PDD-NOS (73.2%). They showed the least developmental progress and highest symptom severity. Results support diagnosing ASDs in children functioning below a 12-month level.

Indexed as

Autism Spectrum DisorderChild DevelopmentChild Development Disorders, PervasiveChild, PreschoolCognitionEarly DiagnosisFemaleFollow-Up StudiesHumansIntellectual DisabilityIntelligenceMaleSocial Behavior DisordersSymptom AssessmentAutism severityAutism spectrum disordersDevelopmental growthDiagnostic stabilityLow mental age

Identifiers

PMID28861732
PMCPMC5845818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.