Evidence map›Paper›PMID 28861670›Full record

ArticleJournal of biomolecular NMR2017

Anthranilic acid, the new player in the ensemble of aromatic residue labeling precursor compounds.

Julia Schörghuber, Leonhard Geist, Marilena Bisaccia, Frederik Weber, Robert Konrat, Roman J Lichtenecker

Abstract read
In one paragraph

Article in Journal of biomolecular NMR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Leveraging relaxation-optimizedNature chemistry · 2025
    Article
  2. Review
  3. Synthesis of aJournal of biomolecular NMR · 2024
    Article
  4. Chemical science · 2023
    Article
  5. Review
  6. Simultaneous measurement ofJournal of biomolecular NMR · 2021
    Article
  7. Article
  8. Site-selectiveJournal of biomolecular NMR · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia SchörghuberInstitute of Organic Chemistry, University of Vienna, Währingerstr. 38, 1090, Vienna, Austria.
Leonhard GeistChristian Doppler Laboratory for High-Content Structural Biology and Biotechnology, Department of Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Dr-Bohr-Gasse 9, 1030, Vienna, Austria.
Marilena BisacciaInstitute of Organic Chemistry, University of Vienna, Währingerstr. 38, 1090, Vienna, Austria.
Frederik WeberInstitute of Organic Chemistry, University of Vienna, Währingerstr. 38, 1090, Vienna, Austria.
Robert KonratChristian Doppler Laboratory for High-Content Structural Biology and Biotechnology, Department of Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Dr-Bohr-Gasse 9, 1030, Vienna, Austria.
Roman J LichteneckerInstitute of Organic Chemistry, University of Vienna, Währingerstr. 38, 1090, Vienna, Austria. roman.lichtenecker@univie.ac.at.

Funding

Universität Wien uni:docs
6 · The paper itself

Abstract

The application of metabolic precursors for selective stable isotope labeling of aromatic residues in cell-based protein overexpression has already resulted in numerous NMR probes to study the structural and dynamic characteristics of proteins. With anthranilic acid, we present the structurally simplest precursor for exclusive tryptophan side chain labeling. A synthetic route to

Indexed as

Isotope LabelingNuclear Magnetic Resonance, Biomolecularortho-AminobenzoatesProteinsTryptophananthranilic acidortho-AminobenzoatesProteinsTryptophanAnthranilic acidIsotope labelingProtein NMRTryptophan

Identifiers

PMID28861670
PMCPMC5626795

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.