Evidence map›Paper›PMID 28861653›Full record

ArticleJournal of autism and developmental disorders2017

Behavioral Phenotype of ASD Preschoolers with Gastrointestinal Symptoms or Food Selectivity.

Margherita Prosperi, Elisa Santocchi, Giulia Balboni, Antonio Narzisi, Margherita Bozza, Francesca Fulceri, Fabio Apicella, Roberta Igliozzi, Angela Cosenza, Raffaella Tancredi and 2 more

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02708901 nacompletednot on this map

Gut to Brain Interaction in Autism. Role of Probiotics on Clinical, Biochemical and Neurophysiological Parameters

TypeinterventionalSponsorIRCCS Fondazione Stella MarisRan2015 to 2018Enrolled85ConditionsAutism Spectrum DisorderArmsVivomixx®, Placebo
NCT06335030 unknown statusnot on this mapstarted 2021, after this paper: background citation

Relationship Between Sensory and Behavioral Aspects With Particular Attention to Food Selectivity in Children With Autism Spectrum Disorder and Parental Stress Perceived

Typeobservational_patient_registrySponsorIRCCS Fondazione Stella MarisRan2021 to 2024Enrolled50ConditionsAutism Spectrum Disorder
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  9. A longitudinal evaluation of gastrointestinal symptoms in children with autism spectrum disorder.Autism : the international journal of research and practice · 2025
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  12. Frontiers in neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Margherita ProsperiIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Elisa SantocchiIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Giulia BalboniUniversity of Perugia, Piazza G. Ermini, 1, 06123, Perugia, Italy.
Antonio NarzisiIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Margherita BozzaStella Maris Mediterraneo Foundation, Chiaromonte, PZ, Italy.
Francesca FulceriIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Fabio ApicellaIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Roberta IgliozziIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Angela CosenzaIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Raffaella TancrediIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Sara CalderoniIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy. sara.calderoni@fsm.unipi.it.
Filippo MuratoriIRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.
Fondazione Stella Maris · ITUniversity of Pisa · ITUniversity of Perugia · IT

Funding

Italian Ministry of Health and Tuscany Region GR-2011-02348280
6 · The paper itself

Abstract

This study investigated the prevalence and type of gastrointestinal (GI) and food selectivity (FS) symptoms in 163 preschoolers with ASD, and their possible links with core ASD features and emotional/behavioural problems. 40.5% of children with ASD had at least one severe GI symptom or FS. Preschoolers with and without GI symptoms and with and without FS were significantly different on several emotional/behavioural problems and restrictive/repetitive behaviours, whereas they did not differ significantly on performance IQ and autistic severity. The GI plus FS group presented with Sleep Problems, Self-injurious Behaviors and Anxiety Problems. Results indicated the need for early identification of GI disturbances and FS in order to design tailored intervention for these symptoms frequently associated to challenging behaviours in ASD.

Indexed as

Food PreferencesAutistic DisorderChildChild BehaviorChild, PreschoolFemaleGastrointestinal DiseasesHumansInfantMalePhenotypeAnxiety ProblemsChild Behavior Checklist 1½–5Externalizing ProblemsRestrictive and repetitive behavioursSleep ProblemsYoung Children

Identifiers

PMID28861653
OpenAlexW2751300432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.