Trial reportJournal of autism and developmental disorders2017
Parent-Mediated Intervention for One-Year-Olds Screened as At-Risk for Autism Spectrum Disorder: A Randomized Controlled Trial.
Trial report in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Parent-Mediated Interventions for ASD Under 3 Years: A Systematic Review, Meta Analysis, and Moderator Analyses.Journal of autism and developmental disorders · 2026Pooled it
- Examining Behavioral Interventions for Infancy and Early Toddlerhood: A Systematic Review of Intervention Effects, Parameters, and Participants.Journal of autism and developmental disorders · 2026Pooled it
- Efficacy of very early interventions on neurodevelopmental outcomes for infants and toddlers at increased likelihood of or diagnosed with autism: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2023Pooled it
- Psychological interventions targeting mental health and the mother-child relationship in autism: Systematic review and meta-analysis.Developmental medicine and child neurology · 2023Pooled it
- Parent-Mediated Interventions for Infants under 24 Months at Risk for Autism Spectrum Disorder: A Systematic Review of Randomized Controlled Trials.Journal of autism and developmental disorders · 2022Pooled it
- Association of Parent Training With Child Language Development: A Systematic Review and Meta-analysis.JAMA pediatrics · 2019Pooled it
- Mediation of 6-year mid-childhood follow-up outcomes after pre-school social communication (PACT) therapy for autistic children: randomised controlled trial.Journal of child psychology and psychiatry, and allied disciplines · 2024Trial
- Teaching Caregivers to Support Social Communication: Results From a Randomized Clinical Trial of Autistic Toddlers.American journal of speech-language pathology · 2023Trial
- A Longitudinal RCT of P-ESDM With and Without Parental Mindfulness Based Stress Reduction: Impact on Child Outcomes.Journal of autism and developmental disorders · 2022Trial
- Caregiver responsiveness as a mechanism to improve social communication in toddlers: Secondary analysis of a randomized controlled trial.Autism research : official journal of the International Society for Autism Research · 2022Trial
- Trial
- Mindfulness-Based Stress Reduction for Parents Implementing Early Intervention for Autism: An RCT.Pediatrics · 2020Trial
- Pathways Early ASD Intervention as a Moderator of Parenting Stress on Parenting Behaviors: A Randomized Control Trial.Journal of autism and developmental disorders · 2019Trial
- A cascading effects model of early sensory development in autism.Psychological review · 2026Review
- Parental Stress and Caregiver Role Modulate Child-Caregiver Prosodic Synchrony in Autism: A Computational Analysis.Autism research : official journal of the International Society for Autism Research · 2026Article
- Optimizing joint engagement in autism: considering toddler developmental abilities and caregiver stress.Frontiers in child and adolescent psychiatry · 2026Article
- Parent-mediated early intervention in infants and toddlers at elevated likelihood for autism: a systematic review of randomized controlled trials.Frontiers in psychiatry · 2026Review
- Increasing dependability of caregiver implementation fidelity estimates in early intervention: A generalizability and decision study.Autism : the international journal of research and practice · 2026Article
- Developmental Impacts of Early Sensory Patterns on School-Age Adaptive, Maladaptive, and Participation Outcomes in Autistic and Non-autistic Children.Journal of autism and developmental disorders · 2025Article
- Measuring Parent-Child Transactions for Early Identification of Young Autistic Children.Journal of autism and developmental disorders · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Theoretically, interventions initiated with at-risk infants prior to the point in time a definitive autism spectrum disorder (ASD) diagnosis can be made will improve outcomes. Pursuing this idea, we tested the efficacy of a parent-mediated early intervention called Adapted Responsive Teaching (ART) via a randomized controlled trial with 87 one-year-olds identified by community screening with the First Year Inventory as at-risk of later ASD diagnoses. We found minimal evidence for main effects of ART on child outcomes. However, ART group parents showed significantly greater increases in responsiveness to their infants than control group parents. Further, significant indirect (mediation) effects of assignment group on multiple child outcomes through changes in parent responsiveness supported our theory of change.
Indexed as
Identifiers
28861651What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.