Evidence map›Paper›PMID 28861622›Full record

ArticleNeuroradiology2017

Perfusion magnetic resonance imaging in pediatric brain tumors.

F Dallery, R Bouzerar, D Michel, C Attencourt, V Promelle, J Peltier, J M Constans, O Balédent, C Gondry-Jouet

Abstract read
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In one paragraph

Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  3. Arterial Spin-Labeling in Children with Brain Tumor: A Meta-Analysis.AJNR. American journal of neuroradiology · 2018
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

F DalleryDepartment of Radiology, University Hospital, Amiens, France. dallery.florine@chu-amiens.fr.
R BouzerarDepartment of Imaging and Biophysics, University Hospital, Amiens, France.
D MichelDepartment of Radiology, University Hospital, Amiens, France.
C AttencourtDepartement of Pathology, University Hospital, Amiens, France.
V PromelleDepartment of Imaging and Biophysics, University Hospital, Amiens, France.
J PeltierDepartement of Neurosurgery, University Hospital, Amiens, France.
J M ConstansDepartment of Radiology, University Hospital, Amiens, France.
O BalédentDepartment of Imaging and Biophysics, University Hospital, Amiens, France.
C Gondry-JouetDepartment of Radiology, University Hospital, Amiens, France.
Centre Hospitalier Universitaire Amiens-Picardie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe use of DSC-MR imaging in pediatric neuroradiology is gradually growing. However, the number of studies listed in the literature remains limited. We propose to assess the perfusion and permeability parameters in pediatric brain tumor grading.

methodsThirty children with a brain tumor having benefited from a DSC-MR perfusion sequence have been retrospectively explored. Relative CBF and CBV were computed on the ROI with the largest lesion coverage. Assessment of the lesion's permeability was also performed through the semi-quantitative PSR parameter and the K2 model-based parameter on the whole-lesion ROI and a reduced ROI drawn on the permeability maps. A statistical comparison of high- and low-grade groups (HG, LG) as well as a ROC analysis was performed on the histogram-based parameters.

resultsOur results showed a statistically significant difference between LG and HG groups for mean rCBV (p < 10

conclusionsThe implementation of a dynamic T2* perfusion sequence provided reliable results using an objective whole-lesion ROI. Perfusion parameters as well as a new permeability indicator could efficiently discriminate high-grade from low-grade lesions in the pediatric population.

Indexed as

AdolescentBrain NeoplasmsChildChild, PreschoolFemaleHumansInfantInfant, NewbornMagnetic Resonance ImagingMaleNeoplasm GradingRetrospective StudiesBrainChildMR perfusionNeoplasmsPermeability

Identifiers

PMID28861622
OpenAlexW2751258642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.