ReviewCannabis and cannabinoid research2017
The Use of Cannabis for Headache Disorders.
Review in Cannabis and cannabinoid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Medical Cannabis for the Treatment of Migraine in Adults: A Review of the Evidence.Frontiers in neurology · 2022Pooled it
- Vaporized cannabis versus placebo for acute migraine: A randomized, double-blind, placebo-controlled crossover trial.Headache · 2026Trial
- Article
- The Exploration of Cannabis and Cannabinoid Therapies for Migraine.Current pain and headache reports · 2023Review
- Medical Cannabis for Headache Pain: a Primer for Clinicians.Current pain and headache reports · 2021Review
- Nutraceuticals and Behavioral Therapy for Headache.Current neurology and neuroscience reports · 2021Review
- A narrative review of the ethnomedicinal usage of Cannabis sativa Linnaeus as traditional phytomedicine by folk medicine practitioners of Bangladesh.Journal of cannabis research · 2021Review
- Review
- Cannabidiol (CBD) for Treatment of Neurofibromatosis-related Pain and Concomitant Mood Disorder: A Case Report.Cureus · 2019Article
- Phytomedicines in the Treatment of Migraine.CNS drugs · 2019Review
- Up-regulation of heme oxygenase-1 expression and inhibition of disease-associated features by cannabidiol in vascular smooth muscle cells.Oncotarget · 2018Article
- [Cannabinoids in pain medicine].Schmerz (Berlin, Germany) · 2018Article
- A Contemporary Perspective on the Management of Post-Craniotomy Headache and Pain.Current pain and headache reports · 2018Review
- Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort.The journal of headache and pain · 2018Article
- Cannabis and pain: a scoping review.Brazilian journal of anesthesiology (Elsevier)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Headache disorders are common, debilitating, and, in many cases, inadequately managed by existing treatments. Although clinical trials of cannabis for neuropathic pain have shown promising results, there has been limited research on its use, specifically for headache disorders. This review considers historical prescription practices, summarizes the existing reports on the use of cannabis for headache, and examines the preclinical literature exploring the role of exogenous and endogenous cannabinoids to alter headache pathophysiology. Currently, there is not enough evidence from well-designed clinical trials to support the use of cannabis for headache, but there are sufficient anecdotal and preliminary results, as well as plausible neurobiological mechanisms, to warrant properly designed clinical trials. Such trials are needed to determine short- and long-term efficacy for specific headache types, compatibility with existing treatments, optimal administration practices, as well as potential risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.