Evidence map›Paper›PMID 28860845›Full record

ReviewJournal of pain research2017

Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic.

Chaoliang Tang, Zhongyuan Xia

2 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05074056 phase4completednot on this mapstarted 2022, after this paper: background citation

Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectom

TypeinterventionalSponsorSt. Louis UniversityRan2022 to 2024Enrolled142ConditionsAdenotonsillar Hypertrophy, Obstructive Sleep Apnea, Sleep-Disordered Breathing, Acute Post Operative PainArmsKetorolac
NCT05534230 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Is Dexmedetomidine Effective at Reducing Pain Scores and Opioid Consumption in Coronary Artery Bypass Grafting (CABG) Patients

TypeinterventionalSponsorWayne State UniversityRan2022 to 2024Enrolled100ConditionsAnalgesiaArmsDexmedetomidine Injectable Solution, Saline
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chaoliang TangDepartment of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Zhongyuan XiaDepartment of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Renmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many nociceptive, inflammatory, and neuropathic pathways contribute to perioperative pain. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies, and dexmedetomidine, in particular, have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. This article reviews the evidence supporting the preoperative, intraoperative, and postoperative efficacy of dexmedetomidine as an adjuvant, and the efficacy of intravenous, spinal canal, and nerve block analgesia with dexmedetomidine for perioperative acute pain treatment. While there have not been any large-scale clinical trials conducted, the current body of evidence suggests that dexmedetomidine is suitable for use as an adjuvant analgesic at all perioperative stages. However, there are potential adverse effects, such as hypotension and bradycardia, which must be taken into consideration by clinicians.

Indexed as

adjuvantanalgesiadexmedetomidinenon-opioidperioperative pain

Identifiers

PMID28860845
PMCPMC5565238
OpenAlexW2744987843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.