Evidence map›Paper›PMID 28860765›Full record

ArticleInternational journal of nanomedicine2017

Silica nanoparticles induce liver fibrosis via TGF-β

Yang Yu, Junchao Duan, Yang Li, Yanbo Li, Li Jing, Man Yang, Ji Wang, Zhiwei Sun

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 86 citations in OpenAlex.

  1. Review
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  3. Enhanced tumor retention and therapeutic potency in radionuclide therapy using GSH-induced self-assembling peptides.Journal of controlled release : official journal of the Controlled Release Society · 2025
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  14. Insights on drug and gene delivery systems in liver fibrosis.Asian journal of pharmaceutical sciences · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Silica Nanoparticle Acute Toxicity on MaleFrontiers in bioengineering and biotechnology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yang YuSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Junchao DuanSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Yang LiSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Yanbo LiSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Li JingSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Man YangSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Ji WangSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Zhiwei SunSchool of Public Health, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liver is one of the target organs of silica nanoparticles (SiO

Indexed as

AnimalsApoptosisCollagenHepatic Stellate CellsHepatocytesInjections, IntravenousLiver CirrhosisMaleMice, Inbred ICRNanoparticlesSignal TransductionSilicon DioxideSmad3 ProteinTransforming Growth Factor beta1CollagenSilicon DioxideSmad3 ProteinSmad3 protein, mouseTransforming Growth Factor beta1fibrosishepatocyte apoptosisoxidative stresssilica nanoparticlesTGF-β1/Smad3 signaling pathway

Identifiers

PMID28860765
PMCPMC5573053
OpenAlexW2749570678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.