Evidence map›Paper›PMID 28860743›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2017

Systematic review of the association between exercise tests and patient-reported outcomes in patients with chronic obstructive pulmonary disease.

Yogesh Suresh Punekar, John H Riley, Emily Lloyd, Maurice Driessen, Sally J Singh

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yogesh Suresh PunekarHealth Outcomes, GlaxoSmithKline, Uxbridge.
John H RileyMDC Global Clinical Development UK, Respiratory Research and Development, GlaxoSmithKline, Uxbridge.
Emily LloydValue Evidence and Outcomes, GlaxoSmithKline, Brentford.
Maurice DriessenMDC Global Clinical Development UK, Respiratory Research and Development, GlaxoSmithKline, Uxbridge.
Sally J SinghCentre for Exercise and Rehabilitation Science, University Hospitals of Leicester NHS Trust, Leicester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic obstructive pulmonary disease (COPD) is an increasingly common cause of death worldwide. Its cardinal symptoms include breathlessness and severely reduced exercise capacity. Several patient-reported outcome (PRO) measures are used to assess health-related quality of life (HRQoL), functional performance, and breathlessness in patients with COPD. Exercise testing is employed to measure functional performance objectively, which is generally believed to impact on overall HRQoL. However, the extent to which commonly used laboratory- and field-based exercise test results correlate with PROs has not been systematically assessed. MATERIALS AND

methodsA search of Embase, MedLine, and the Cochrane Library identified primary publications in English that reported data on the correlations (Pearson's

resultsOf 3,205 articles screened, 28 were deemed eligible for inclusion. The most commonly reported HRQoL PRO measure was the St George's Respiratory Questionnaire (13 studies), and the most commonly reported breathlessness PRO measure was the Baseline Dyspnea Index (six studies). The St George's Respiratory Questionnaire appears to correlate very weakly to moderately with the 6MWT, and breathlessness PROs appear to be moderately to strongly associated with 6MWT outcomes. Across all studies, the 6MWT was the most commonly reported exercise test. Very few publications reporting associations between other exercise tests and PRO measures were found.

conclusionThis review found evidence to support the association of 6MWT outcomes with HRQoL and breathlessness PROs. There were limited data showing correlations with the outcomes of other exercise tests. Further work is required to examine the associations between these PROs and exercise test outcomes.

Indexed as

Exercise TestExercise TolerancePatient Reported Outcome MeasuresAgedBicyclingFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPredictive Value of TestsPulmonary Disease, Chronic ObstructiveQuality of LifeReproducibility of ResultsSeverity of Illness IndexCOPDexercise testspatient-reported outcomes

Identifiers

PMID28860743
PMCPMC5573061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.