ArticleScientific reports2017
Chill coma in the locust, Locusta migratoria, is initiated by spreading depolarization in the central nervous system.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 81 citations in OpenAlex.
- Detection and Quantification of Spreading Depolarization in Drosophila melanogaster Using High-Throughput, Wide-Field Brain Imaging.Current protocols · 2026Article
- Whole brain fluorescence imaging iniScience · 2026Article
- Gene Expression Associated With Behaviour Manipulation in Wood Ants Infected With Larval Lancet Fluke, Dicrocoelium dendriticum.Molecular ecology · 2025Article
- The caterpillar Manduca sexta brain shows changes in gene expression and protein abundance correlating with parasitic manipulation of behaviour.Scientific reports · 2024Article
- Genome-wide DNA methylation patterns in bumble bee (Bombus vosnesenskii) populations from spatial-environmental range extremes.Scientific reports · 2023Article
- In vivo closed-loop control of a locust's leg using nerve stimulation.Scientific reports · 2022Article
- A lack of repeatability creates the illusion of a trade-off between basal and plastic cold tolerance.Proceedings. Biological sciences · 2021Article
- Body mass and sex, not local climate, drive differences in chill coma recovery times in common garden reared bumble bees.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
- Fly seizure EEG: field potential activity in theJournal of neurogenetics · 2021Article
- Hyperkalaemia, not apoptosis, accurately predicts insect chilling injury.Proceedings. Biological sciences · 2020Article
- Article
- Neural shutdown under stress: an evolutionary perspective on spreading depolarization.Journal of neurophysiology · 2020Review
- Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of chill-sensitive insects to function at low temperatures limits their geographic ranges. They have species-specific temperatures below which movements become uncoordinated prior to entering a reversible state of neuromuscular paralysis. In spite of decades of research, which in recent years has focused on muscle function, the role of neural mechanisms in determining chill coma is unknown. Spreading depolarization (SD) is a phenomenon that causes a shutdown of neural function in the integrating centres of the central nervous system. We investigated the role of SD in the process of entering chill coma in the locust, Locusta migratoria. We used thermolimit respirometry and electromyography in whole animals and extracellular and intracellular recording techniques in semi-intact preparations to characterize neural events during chilling. We show that chill-induced SD in the central nervous system is the mechanism underlying the critical thermal minimum for coordinated movement in locusts. This finding will be important for understanding how insects adapt and acclimate to changing environmental temperatures.
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