ArticleAmerican journal of human genetics1987
Human homeo box-containing genes located at chromosome regions 2q31----2q37 and 12q12----12q13.
Article in American journal of human genetics, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 75 citations in OpenAlex.
- Hyperexpression of HOXC13, located in the 12q13 chromosomal region, in well‑differentiated and dedifferentiated human liposarcomas.Oncology reports · 2013Article
- High-resolution transcript map of the region spanning D12S1629 and D12S312 at chromosome 12q13: triple A syndrome-linked region.Genome research · 2000Article
- Dinucleotide repeats in the mouse Hox-4.4 and Hox-4.5 genes on chromosome 2, and their analysis in the BXD and BXH recombinant inbred strains.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.The EMBO journal · 1991Article
- Syndromes associated with simple calvarial and complex craniofacial anomalies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 1991Review
- Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.American journal of human genetics · 1991Article
- Comparative map for mice and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Mouse chromosome 2.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- The human VAV proto-oncogene maps to chromosome region 19p12----19p13.2.Human genetics · 1990Article
- Chromosomes 17 and 22 involved in marker formation in neurofibrosarcoma in von Recklinghausen disease. A cytogenetic and in situ hybridization study.Human genetics · 1990Article
- Isolation of a cDNA clone encoding a novel form of granzyme B from human NK cells and mapping to chromosome 14.Human genetics · 1990Article
- The human HOX gene family.Nucleic acids research · 1989Article
- Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- Two type II keratin genes are localized on human chromosome 12.Human genetics · 1989Article
- Chromosomal translocation in T-cell leukemia line HUT 78 results in a MYC fusion transcript.Proceedings of the National Academy of Sciences of the United States of America · 1988Article
- Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos.The EMBO journal · 1988Article
- Mapping of the human retinoic acid receptor to the q21 band of chromosome 17.Human genetics · 1988Article
- Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22.Proceedings of the National Academy of Sciences of the United States of America · 1988Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Four human homeo box-containing cDNAs isolated from mRNA of an SV40-transformed human fibroblast cell line have been regionally localized on the human gene map. One cDNA clone, c10, was found to be nearly identical to the previously mapped Hox-2.1 gene at 17q21. A second cDNA clone, c1, which is 87% homologous to Hox-2.2 at the nucleotide level but is distinct from Hox-2.1 and Hox-2.2, also maps to this region of human chromosome 17 and is probably another member of the Hox-2 cluster of homeo box-containing genes. The third cDNA clone, c8, in which the homeo box is approximately 84% homologous to the mouse Hox-1.1 homeo box region on mouse chromosome 6, maps to chromosome region 12q12----12q13, a region that is involved in chromosome abnormalities in human seminomas and teratomas. The fourth cDNA clone, c13, whose homeo box is approximately 73% homologous to the Hox-2.2 homeo box sequence, is located at chromosome region 2q31----q37. The human homeo box-containing cluster of genes at chromosome region 17q21 is the human cognate of the mouse homeo box-containing gene cluster on mouse chromosome 11. Other mouse homeo box-containing genes of the Antennapedia class (class I) map to mouse chromosomes 6 (Hox-1, proximal to the IgK locus) and 15 (Hox-3). A mouse gene, En-1, with an engrailed-like homeo box (class II) and flanking region maps to mouse chromosome 1 (near the dominant hemimelia gene). Neither of the class I homeo box-containing genes--c8 and c13--maps to a region of obvious homology to chromosomal positions of the presently known mouse homeo box-containing genes.
Indexed as
Identifiers
2886047PMC1684175W1508786192What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.