Evidence map›Paper›PMID 28860458›Full record

ArticleScientific reports2017

Intracellular Chloride Regulation in AVP+ and VIP+ Neurons of the Suprachiasmatic Nucleus.

Nathan J Klett, Charles N Allen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. One seasonal clock fits all?Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Role of the cation-chloride-cotransporters in the circadian system.Asian journal of pharmaceutical sciences · 2021
    Review
  8. Article
  9. Diurnal properties of tonic and synaptic GABAJournal of neurophysiology · 2021
    Article
  10. Review
  11. Review
  12. Distal convoluted tubule ClAmerican journal of physiology. Renal physiology · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nathan J KlettNeuroscience Graduate Program, School of Medicine, Oregon Health & Science University, Portland, OR, 97239, USA.ORCID 0000-0002-7102-1728
Charles N AllenOregon Institute for Occupational Health Sciences, School of Medicine, Oregon Health & Science University, Portland, OR, 97239, USA. allenc@ohsu.edu.
Oregon Health & Science University · US

Funding

CELLULAR ELECTROPHYSIOLOGY OF THE SUPRACHIASMATIC NUCLEIR01NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 1998 to 2015
$4.4M
Cellular Electrophysiology of the Suprachiasmatic NucleiR56NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 2011 to 2017
$1.1M
NINDS NIH HHS R01 NS036607NINDS NIH HHS R56 NS036607
6 · The paper itself

Abstract

Several reports have described excitatory GABA transmission in the suprachiasmatic nucleus (SCN), the master pacemaker of circadian physiology. However, there is disagreement regarding the prevalence, timing, and neuronal location of excitatory GABA transmission in the SCN. Whether GABA is inhibitory or excitatory depends, in part, on the intracellular concentration of chloride ([Cl

Indexed as

AnimalsBumetanideChloridesK Cl- CotransportersMaleMiceMice, Inbred C57BLReceptors, GABA-ASolute Carrier Family 12, Member 2Suprachiasmatic Nucleus NeuronsSymportersThiazolesThioglycolatesVasoactive Intestinal PeptideVasopressinsBumetanideChloridesK Cl- CotransportersN-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamideReceptors, GABA-ASlc12a2 protein, mouseSolute Carrier Family 12, Member 2SymportersThiazolesThioglycolatesVasoactive Intestinal PeptideVasopressins

Identifiers

PMID28860458
PMCPMC5579040
OpenAlexW2745655002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.