ReviewJournal of neurology, neurosurgery, and psychiatry2017
The screening and management of pituitary dysfunction following traumatic brain injury in adults: British Neurotrauma Group guidance.
Review in Journal of neurology, neurosurgery, and psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Equity considerations in clinical practice guidelines for traumatic brain injury and the criminal justice system: A systematic review.PLoS medicine · 2024Pooled it
- Long-term Empagliflozin Use in Chronic Syndrome of Inappropriate Antidiuresis Due to Traumatic Subarachnoid Hemorrhage.JCEM case reports · 2026Article
- Article
- Navigating anterior pituitary dysfunction after traumatic brain injury: mechanisms, diagnosis, and management.Acta neurologica Belgica · 2025Review
- Diagnostic Value of Serum Biomarkers in Endocrine Dysfunction, Neuronal Injury, and Inflammation Following Traumatic Brain Injury.International journal of molecular sciences · 2025Review
- Multiphase management of sodium imbalance following traumatic brain injury: a case-based review.BMC pediatrics · 2025Review
- Dynamics of anterior pituitary function in the acute phase of traumatic brain injury: a prospective cohort.Critical care science · 2025Article
- IGF-1 as a Biomarker for Symptom Severity in Adult Traumatic Brain Injury: Evidence from an Observational Study.Neurotrauma reports · 2025Article
- Delayed onset arginine vasopressin deficiency after traumatic brain injury.Endocrinology, diabetes & metabolism case reports · 2024Article
- Neuroendocrine challenges and clinical outcomes in men with chronic traumatic brain injury: a cross-sectional study.Pituitary · 2024Article
- Morbidities and mortality among hospitalized patients with hypopituitarism: Prevalence, causes and management.Reviews in endocrine & metabolic disorders · 2024Review
- Recognition and Practice of Hypopituitarism After Traumatic Brain Injury and Subarachnoid Hemorrhage in Japan: A Survey.Neurology and therapy · 2024Article
- Traumatic brain injury inducing swift transition from syndrome of inappropriate antidiuretic hormone secretion to central diabetes insipidus: a case report.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2024Article
- Acute neuroendocrine changes after traumatic brain injury.Brain & spine · 2024Review
- Article
- Endocrine Dysfunction After Traumatic Brain Injury: An Ignored Clinical Syndrome?Neurocritical care · 2023Review
- Neuroendocrine Disruptions Following Head Injury.Current neurology and neuroscience reports · 2023Review
- An Approach to Traumatic Brain Injury-Related Hypopituitarism: Overcoming the Pediatric Challenges.Diagnostics (Basel, Switzerland) · 2023Article
- Hypopituitary syndrome with pituitary crisis in a patient with traumatic shock: A case report.World journal of clinical cases · 2022Article
- NZ-RugbyHealth Study: Self-reported Injury Experience and Current Health of Former Rugby Union and Non-contact Sport Players.Sports medicine (Auckland, N.Z.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 8 institutions in 1 country.
Funding
Abstract
Pituitary dysfunction is a recognised, but potentially underdiagnosed complication of traumatic brain injury (TBI). Post-traumatic hypopituitarism (PTHP) can have major consequences for patients physically, psychologically, emotionally and socially, leading to reduced quality of life, depression and poor rehabilitation outcome. However, studies on the incidence of PTHP have yielded highly variable findings. The risk factors and pathophysiology of this condition are also not yet fully understood. There is currently no national consensus for the screening and detection of PTHP in patients with TBI, with practice likely varying significantly between centres. In view of this, a guidance development group consisting of expert clinicians involved in the care of patients with TBI, including neurosurgeons, neurologists, neurointensivists and endocrinologists, was convened to formulate national guidance with the aim of facilitating consistency and uniformity in the care of patients with TBI, and ensuring timely detection or exclusion of PTHP where appropriate. This article summarises the current literature on PTHP, and sets out guidance for the screening and management of pituitary dysfunction in adult patients with TBI. It is hoped that future research will lead to more definitive recommendations in the form of guidelines.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.