Evidence map›Paper›PMID 28860265›Full record

ReviewThe European respiratory journal2017

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure.

Bram Rochwerg, Laurent Brochard, Mark W Elliott, Dean Hess, Nicholas S Hill, Stefano Nava, Paolo Navalesi, Massimo Antonelli, Jan Brozek, Giorgio Conti and 7 more

16 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 16 registered trials, which are not on this map. Cited by 657 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
657citing papers in PubMed, 14 pooled it
98.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03458364 nacompletednot on this map

Comparison of High Flow Nasal Cannula With Noninvasive Ventilation in Facilitating Weaning Chronic Obstructive Pulmonary Disease From Invasive Ventilation: a Prospective Randomized Controlled Study

TypeinterventionalSponsorJie LiRan2017 to 2018Enrolled42ConditionsChronic Obstructive Pulmonary Disease With (Acute) ExacerbationArmsHigh flow nasal cannula, Noninvasive ventilation
NCT03728452 completednot on this mapstarted 2019, after this paper: background citation

Trophic Nutrition in Patients Submitted to High Flow Oxygen Therapy and / or Non Invasive

TypeobservationalSponsorHospital San Carlos, MadridRan2019 to 2024Enrolled149ConditionsNoninvasive Ventilation, Trophic NutritionArmsTrophic Nutrition
NCT04052542 nacompletednot on this mapstarted 2019, after this paper: background citation

Maximizing Extubation Outcomes Through Educational and Organizational Research: Think NIV Pilot Study

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2019Enrolled1,328ConditionsAcute Respiratory FailureArmsTraditional online continuing education, Interprofessional education, Just-in-time education
NCT04427826 phase1 / phase2recruitingnot on this mapstarted 2020, after this paper: background citation

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation (NIV) Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD), Phase I/IIa

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2020 to 2028Enrolled24ConditionsChronic Obstructive Pulmonary DiseaseArmsMorphine hydrochloride
NCT04780503 completednot on this mapstarted 2020, after this paper: background citation

The Rapid Shallow Breathing Index as an Early Predictor for Intubation and Mortality in Patients Undergoing Non-invasive Mechanical Ventilation in Acute Respiratory Failure

TypeobservationalSponsorIzmir Katip Celebi UniversityRan2020 to 2021Enrolled267ConditionsAcute Respiratory FailureArmsRapid Shallow Breathing Index
NCT04998383 naunknown statusnot on this mapstarted 2021, after this paper: background citation

HVNI vs Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure

TypeinterventionalSponsorAssiut UniversityRan2021 to 2022Enrolled100ConditionsComparison Between HVNI vs Noninvasive Ventilation for Acute Hypercapnic Respiratory FailureArmsHVNI
NCT05012696 nacompletednot on this mapstarted 2021, after this paper: background citation

Postextubation Non-invasive Ventilation Versus High-flow Nasal Cannula in Critically Ill Patients at High Risk of Weaning Failure: a Physiologic Randomized Crossover Study

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2021 to 2024Enrolled22ConditionsWeaning From Mechanical VentilationArmsNon-invasive ventilation (NIV), High-flow nasal cannula
NCT05513508 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Pragmatic Open Label, Multi-center, Spontaneous, No-profit, Randomized Controlled Clinical Trial With Non-significant Risk Medical Device on the Rotational Use of Interfaces Versus Standard of Care for Patients Treated With NPPV for AHRF.

TypeinterventionalSponsorAzienda Ospedaliero Universitaria Maggiore della CaritaRan2022 to 2028Enrolled478ConditionsPressure Ulcer, Noninvasive Positive Pressure Ventilation, Acute Hypercapnic Respiratory FailureArmsProtocolized rotational use of interfaces, Standard of care
NCT05523479 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

TypeinterventionalSponsorUniversity of PittsburghRan2023 to 2026Enrolled13,018ConditionsAcute Respiratory Failure, Airway ExtubationArmsTraditional online education, Interprofessional education, Clinical protocol, Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC), Preventive post-extubation high-flow nasal cannula oxygen (HFNC)
NCT05576246 nacompletednot on this mapstarted 2022, after this paper: background citation

Airway Occlusion Measured During Non-invasive Ventilation to Assess Respiratory Effort

TypeinterventionalSponsorClinica Olivos SMGRan2022 to 2025Enrolled12ConditionsHealthy VolunteersArmsairway pressure occlusion measurement
NCT06489379 naunknown statusnot on this mapstarted 2024, after this paper: background citation

High Flow Nasal Oxygen for Acute Hypoxemic Respiratory Failure in the Emergency Room: the GLAMOUR Study

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2024 to 2026Enrolled234ConditionsRespiratory Distress Syndrome, AdultArmshigh flow nasal cannula, standard oxygen
NCT06837402 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Epidemiology of Non- Invasive Mechanical Ventilation in Argentina: a Multicenter Observational Study

TypeobservationalSponsorArgentinian Intensive Care SocietyRan2025 to 2026Enrolled246ConditionsRespiration, Artificial, Noninvasive Ventilation, Intensive Care Units
NCT06996197 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation of Bioelectric Impedance Analysis in Non-invasive Ventilated Patients With Acute Respiratory Failure: The NIVAR Study

TypeinterventionalSponsorHospital Universitari de BellvitgeRan2021 to 2022Enrolled74ConditionsHypoxemic Acute Respiratory Failure, Non Invasive Ventilation (NIV), Bioimpedance Measurement CapacityArmsBioimpedance analysis
NCT07067502 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Biphasic Cuirass Ventilation Compared to Non-Invasive Ventilation in High Risk Extubations

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2026 to 2027Enrolled50ConditionsRespiratory Failure, Extubation FailureArmsBiphasic cuirass ventilator which is a type of negative pressure ventilator will be applied to patients on the intervention arm
NCT07081776 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of the Effects on Carbon Dioxide (paCO2) of a New Oronasal Mask in Patients With Severe Exacerbation of COPD Requiring Non-Invasive Mechanical Ventilation: A Single-Center, Exploratory, Randomized Cross-Over Study

TypeinterventionalSponsorIRCCS Azienda Ospedaliero-Universitaria di BolognaRan2025 to 2027Enrolled21ConditionsCOPD, Respiratory AcidosisArmsOptiNIV, Visairo
NCT07508943 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Decision-making and Optimization of Ventilatory Support for AECOPD Patients

TypeobservationalSponsorSir Run Run Shaw HospitalRan2026 to 2029Enrolled1,000ConditionsAcute Exacerbation of Chronic Obstructive Pulmonary Disease
3 · Its place in the literature

Who cites it

657 citing papers in PubMed, 14 syntheses or guidelines pooled it, 1,572 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Guideline
  11. Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Guideline
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

597 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 15 institutions in 6 countries.

Bram RochwergDept of Medicine, Dept of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-8293-7061
Laurent BrochardInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Mark W ElliottDept of Respiratory Medicine, St James's University Hospital, Leeds, UK.
Dean HessRespiratory Care Dept, Massachusetts General Hospital and Dept of Anesthesia, Harvard Medical School, Boston, MA, USA.
Nicholas S HillDivision of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA.
Stefano NavaDept of Specialistic, Diagnostic and Experimental Medicine, Respiratory and Critical Care, Sant'Orsola Malpighi Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy Stefanava@gmail.com.
Paolo NavalesiAnesthesia and Intensive Care, Dept of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Massimo AntonelliDept of Anesthesiology and Intensive Care Medicine, Catholic University of Rome, A. Gemelli University Hospital, Rome, Italy.
Jan BrozekDept of Medicine, Dept of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
Giorgio ContiDept of Anesthesiology and Intensive Care Medicine, Catholic University of Rome, A. Gemelli University Hospital, Rome, Italy.
Miquel FerrerDept of Pneumology, Respiratory Institute, Hospital Clinic, IDIBAPS, University of Barcelona and CIBERES, Barcelona, Spain.
Kalpalatha GuntupalliDepts of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA.
Samir JaberDept of Critical Care Medicine and Anesthesiology (DAR B), Research Unit INSERM U1046, Saint Eloi University Hospital and Montpellier School of Medicine, Montpellier, France.
Sean KeenanDivision of Critical Care Medicine, University of British Columbia, Vancouver, BC, Canada.
Jordi ManceboServei de Medicina Intensiva, Hospital de Sant Pau, Barcelona, Spain.
Sangeeta MehtaMount Sinai Hospital and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Suhail RaoofPulmonary and Critical Care Medicine, Lenox Hill Hospital, New York, NY, USA.
Agostino Gemelli University Polyclinic · ITMcMaster University · CABaylor College of Medicine · USCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESHarvard University · USHofstra University · USHospital de Sant Pau · ESInserm · FRIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITMagna Graecia University · ITMount Sinai Hospital · CARoyal Columbian Hospital · CASt James's University Hospital · GBSt. Michael's Hospital · CATufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies. This document provides European Respiratory Society/American Thoracic Society recommendations for the clinical application of NIV based on the most current literature.The guideline committee was composed of clinicians, methodologists and experts in the field of NIV. The committee developed recommendations based on the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology for each actionable question. The GRADE Evidence to Decision framework in the guideline development tool was used to generate recommendations. A number of topics were addressed using technical summaries without recommendations and these are discussed in the supplementary material.This guideline committee developed recommendations for 11 actionable questions in a PICO (population-intervention-comparison-outcome) format, all addressing the use of NIV for various aetiologies of ARF. The specific conditions where recommendations were made include exacerbation of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema,

Indexed as

Respiratory InsufficiencyAcute DiseaseCritical CareDiagnosis, DifferentialHumansNoninvasive VentilationPractice Guidelines as Topic

Identifiers

PMID28860265
OpenAlexW2753000083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 10 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.