Evidence map›Paper›PMID 28860264›Full record

Trial reportThe European respiratory journal2017

Adaptive servo ventilation for central sleep apnoea in heart failure: SERVE-HF on-treatment analysis.

Holger Woehrle, Martin R Cowie, Christine Eulenburg, Anna Suling, Christiane Angermann, Marie-Pia d'Ortho, Erland Erdmann, Patrick Levy, Anita K Simonds, Virend K Somers and 3 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00733343 (Treatment of Sleep-Disordered Breathing With Predominant Central Sleep Apnea by Adaptive Servo Ventilation in Patients With Heart Failure), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00733343 nacompletednot on this map

Treatment of Sleep-Disordered Breathing With Predominant Central Sleep Apnea by Adaptive Servo Ventilation in Patients With Heart Failure

TypeinterventionalSponsorResMedRan2008 to 2015Enrolled1,325ConditionsHeart Failure, Sleep Disordered BreathingArmsEurope: AutoSet CS (USA: VPAP Adapt SV)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Sleep-Related Breathing Disorders: When CPAP Is Not Enough.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  9. Effect of Treatment of Central Sleep Apnea/Cheyne-Stokes Respiration on Left Ventricular Ejection Fraction in Heart Failure: A Network Meta-Analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  10. Observational
  11. Article
  12. Article
  13. Sleep Apnea and Heart Failure With a Reduced Ejection Fraction Among Persons Living With Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Holger WoehrleResMed Science Center, ResMed Germany Inc., Martinsried, Germany hwoehrle@lungenzentrum-ulm.de.
Martin R CowieImperial College London, London, UK.
Christine EulenburgDepartment of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands.
Anna SulingDepartment of Medical Biometry and Epidemiology, University Medical Center Eppendorf, Hamburg, Germany.
Christiane AngermannDepartment of Medicine I and Comprehensive Heart Failure Center, University Hospital and University of Würzburg, Würzburg, Germany.
Marie-Pia d'OrthoUniversity Paris Diderot, Sorbonne Paris Cité, Hôpital Bichat, Explorations Fonctionnelles, DHU FIRE, AP-HP, Paris, France.
Erland ErdmannHeart Center, University of Cologne, Cologne, Germany.
Patrick LevyCHU de Grenoble, Grenoble, France.
Anita K SimondsRoyal Brompton Hospital, London, UK.
Virend K SomersMayo Clinic and Mayo Foundation, Rochester, MN, USA.
Faiez ZannadINSERM, Université de Lorraine, CHU Nancy, France.
Helmut TeschlerDepartment of Pneumology, Ruhrlandklinik, West German Lung Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Karl WegscheiderDepartment of Medical Biometry and Epidemiology, University Medical Center Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This on-treatment analysis was conducted to facilitate understanding of mechanisms underlying the increased risk of all-cause and cardiovascular mortality in heart failure patients with reduced ejection fraction and predominant central sleep apnoea randomised to adaptive servo ventilation

Indexed as

Heart FailureSleep Apnea, CentralCardiovascular DiseasesCause of DeathContinuous Positive Airway PressureFemaleHumansIntention to Treat AnalysisMaleMiddle AgedRisk FactorsStroke VolumeVentricular Dysfunction, Left

Identifiers

PMID28860264
PMCPMC5593355

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.