Evidence map›Paper›PMID 28859658›Full record

SynthesisInternational journal for equity in health2017

The effect of socioeconomic disadvantage on prescription of guideline-recommended medications for patients with acute coronary syndrome: systematic review and meta-analysis.

Karice K Hyun, David Brieger, Mark Woodward, Sarah Richtering, Julie Redfern

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal for equity in health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Income and antiplatelet adherence following percutaneous coronary intervention.International journal of cardiology. Cardiovascular risk and prevention · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Karice K HyunSydney Medical School, University of Sydney, Sydney, Australia. khyun@georgeinstitute.org.au.
David BriegerDepartment of Cardiology, Concord Hospital, University of Sydney, Sydney, Australia.
Mark WoodwardThe George Institute for Global Health, Sydney, Australia.
Sarah RichteringGeneva University Hospital, Geneva, Switzerland.
Julie RedfernThe George Institute for Global Health, Sydney, Australia.
The George Institute for Global Health · AUConcord Repatriation General Hospital · AUUniversity Hospital of Geneva · CHUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are varying data on whether socioeconomic status (SES) affects the treatment in patients with acute coronary syndrome (ACS). Our aim was to obtain a reliable estimate of the effect of SES on discharge prescription of medications following an ACS through systematic review and meta-analysis.

methodsMedline, EMBASE and Global Health were searched systematically on 6th April 2016. Studies were eligible if the participants had ACS and reported the rate/odds of guideline-recommended ACS medications prescription (aspirin, antiplatelet, beta blocker, angiotensin co-enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB) and statin) at discharge stratified by SES. A meta-analysis was performed to pool the estimates, comparing the prescription ratio (PR) between the lowest and the highest SES groups.

resultsOf 252 articles found from the search, seven met the eligibility criteria and it included 41,462 (20,986 from the lowest SES group) patients. We found that the individual/neighbourhood level SES did not affect the prescription of aspirin (PR (95% CI): 0.97 (0.91, 1.03)), but for beta blocker and statin, the lowest SES group were disadvantaged (0.84 (0.73, 0.94), 0.80 (0.62, 0.98), respectively). In contrast, ACEi were prescribed more often to the lowest individual/neighbourhood level SES group than the highest (1.13 (1.05, 1.22)). Although the risk of bias was low, there was considerable heterogeneity between the studies.

conclusionsDespite the recommendations to close the treatment gap, the rate of prescription of guideline-recommended medications in managing ACS is significantly different between patients with the lowest and the highest groups. A solution is needed to provide equitable care across the SES groups. PROSPERO REGISTRY: Systematic review registration no.: CRD42016048503. Registered 28 September 2016.

Indexed as

Healthcare DisparitiesSocial ClassAcute Coronary SyndromeDrug PrescriptionsHumansPractice Guidelines as TopicAcute coronary syndromeHealth inequityIn-hospital careMedication prescriptionSocioeconomic statusSystematic review

Identifiers

PMID28859658
PMCPMC5579970
OpenAlexW2753447900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.