SynthesisBMC anesthesiology2017
The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis.
Synthesis in BMC anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 115 citations in OpenAlex.
- The obesity paradox in murine sepsis models: a systematic review and meta-analysis.Anaesthesiology intensive therapy · 2025Pooled it
- Impact of underweight status on mortality in sepsis patients: a meta-analysis.Frontiers in medicine · 2025Pooled it
- Exploring the relationship between life course adiposity and sepsis: insights from a two-sample Mendelian randomization analysis.Frontiers in endocrinology · 2024Pooled it
- The Effects of Obesity on Outcome in Preclinical Animal Models of Infection and Sepsis: A Systematic Review and Meta-Analysis.Journal of obesity · 2020Pooled it
- A nomogram to predict prolonged stay of obesity patients with sepsis in ICU: Relevancy for predictive, personalized, preventive, and participatory healthcare strategies.Frontiers in public health · 2022Trial
- Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study.PLoS medicine · 2020Trial
- Dynamic trajectories of serum sodium and urine output and their association with prognosis in sepsis: a group-based multi-trajectory modelling analysis using MIMIC-IV.Journal of global health · 2026Article
- The prognostic value of CT-quantified visceral and subcutaneous fat areas in sepsis.World journal of emergency medicine · 2026Article
- Association of obesity and nutritional status on early sepsis-associated acute kidney injury in older patients with sepsis.BMC nephrology · 2026Article
- Association between body mass index and mortality in intensive care unit patients with sepsis: A retrospective cohort study.Scientific reports · 2026Article
- Association of Body Mass Index with 28-Day Mortality in Adult Intensive Care Patients with Sepsis: A Retrospective Observational Study.Sisli Etfal Hastanesi tip bulteni · 2026Article
- Advanced lung cancer inflammation index and all-cause mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database.BMC infectious diseases · 2025Observational
- Comparative Analysis of Sepsis Outcomes Across Body Mass Index Groups: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- The Impact of Biological Sex And High-Fat High-Fructose Diet on Brain Dysfunction in an Animal Model of Sepsis.Molecular neurobiology · 2025Article
- Machine learning algorithms for risk factor selection with application to 60-day sepsis morbidity risk for a geriatric hip fracture cohort.BMC geriatrics · 2025Article
- The role of adipose tissue in critical illness-induced skeletal muscle wasting-new considerations for treatment approaches.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Review
- Harnessing adiponectin for sepsis: current knowledge, clinical insights and future therapies.Critical care (London, England) · 2025Review
- Association between advanced lung cancer inflammation index and all-cause mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database.Scientific reports · 2025Article
- Survival analysis for sepsis patients: A machine learning approach to feature selection and predictive modeling.Scientific reports · 2025Article
- Association between advanced lung cancer inflammation index and mortality in critically ill septic patients: analysis of the MIMIC-IV database.BMC infectious diseases · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of increased body mass index (BMI) in sepsis is controversial. We aimed to evaluate the associations between overweight (25 kg/m
methodsWe searched the PubMed, Embase, Web of Science, Cochrane Library and ClinicalTrials.gov databases for studies published by December 1, 2016. Electronic database searches yielded 3713 articles, eight of which were included in this meta-analysis. Data were independently extracted by two reviewers, and a third reviewer participated in making decisions as needed. We used Review Manager to conduct the analysis, and the outcomes were reported with odds ratios (ORs) or mean differences (MDs). The primary outcome was mortality, and the secondary outcome was length of stay (LOS) in the intensive care unit (ICU) or the hospital.
resultsData from eight studies involving a total of 9696 patients were pooled in our final analysis. Compared with patients with normal BMI (18.5 kg/m
conclusionsIn sepsis cases, overweight, but not obesity or morbid obesity, was associated with lower mortality. Further prospective studies are needed to clarify this relationship.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.