ArticlePloS one2017
An association of cognitive impairment with diabetes and retinopathy in end stage renal disease patients under peritoneal dialysis.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Prevalence of cognitive impairment and its predictors among chronic kidney disease patients: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Prevalence of cognitive impairment among peritoneal dialysis patients: a systematic review and meta-analysis.Clinical and experimental nephrology · 2019Pooled it
- Type 2 Diabetes Mellitus Is Associated with the Risk of Cognitive Impairment: a Meta-Analysis.Journal of molecular neuroscience : MN · 2019Pooled it
- Crosstalk of kidney and brain in diabetes-related cognitive impairment and therapeutic strategies.Frontiers in endocrinology · 2025Review
- Retinopathy is associated with impaired cognition in patients undergoing peritoneal dialysis.Renal failure · 2023Observational
- Age-Related Eye Diseases in Individuals With Mild Cognitive Impairment and Alzheimer's Disease.Frontiers in aging neuroscience · 2022Article
- Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction.International journal of molecular sciences · 2021Review
- The Contribution of Kidney Disease to Cognitive Impairment in Patients with Type 2 Diabetes.Current diabetes reports · 2020Review
- The relationship between cognitive function and having diabetes in patients treated with hemodialysis.International journal of nursing sciences · 2020Article
- Altered Intrinsic Brain Activities in Patients with Diabetic Retinopathy Using Amplitude of Low-frequency Fluctuation: A Resting-state fMRI Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Prevalence and Prognosis of Coexisting Frailty and Cognitive Impairment in Patients on Continuous Ambulatory Peritoneal Dialysis.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes and retinopathy have been considered as risk factors of cognitive impairment (CI) in previous studies. We investigated both of these two factors and their relationship with global and specific cognitive functions in end stage renal disease patients under peritoneal dialysis (PD).
methodsIn this multicenter cross-sectional study, 424 clinically stable patients were enrolled from 5 PD units, who performed PD for at least three months and completed fundoscopy examination if they had diabetes. Global cognitive function was measured using the Modified Mini-Mental State Examination (3MS), Trail-Making Test forms A and B for executive function, and subtests of the Battery for the Assessment of Neuropsychological Status for immediate and delayed memory, visuospatial skills, and language ability.
resultsPD Patients with DM and Retinopathy had significantly higher prevalence of CI, executive dysfunction, impaired immediate memory and visuospatial skill, compared with patients in non-DM group. By multivariate logistic regression analyses, DM and retinopathy rather than DM only were significantly associated with increased risk for CI, executive dysfunction, impaired immediate memory and visuospatial skill, odds ratios(ORs) and 95% confidence intervals were 2.09[1.11,3.92], 2.89[1.55,5.37], 2.16 [1.15,4.06] and 2.37[1.32,4.22], respectively (all P < 0.05).
conclusionsDiabetic PD patients with retinopathy were at two times risk for overall cognitive impairment, executive dysfunction, impaired immediate memory and visuospatial skill as compared to non-diabetic PD patients.
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