Evidence map›Paper›PMID 28858758›Full record

ArticleEnvironmental research2017

Livestock and poultry density and childhood cancer incidence in nine states in the USA.

Benjamin J Booth, Rena R Jones, Mary E Turyk, Sally Freels, Deven M Patel, Leslie T Stayner, Mary H Ward

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Environmental Hazards and Glial Brain Tumors: Association or Causation?International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Benjamin J BoothOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 9609 Medical Center Dr., Room 6E138, Rockville, MD 20850, USA; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA.
Rena R JonesOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 9609 Medical Center Dr., Room 6E138, Rockville, MD 20850, USA.
Mary E TurykDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA.
Sally FreelsDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA.
Deven M PatelOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 9609 Medical Center Dr., Room 6E138, Rockville, MD 20850, USA.
Leslie T StaynerDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA.
Mary H WardOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 9609 Medical Center Dr., Room 6E138, Rockville, MD 20850, USA. Electronic address: wardm@mail.nih.gov.
National Institutes of Health · USUniversity of Illinois Chicago · US

Funding

Cancer Risk and Environmental ExposuresZIACP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$41.3M
Occupational Safety and Health, ERC, University of Illinois at ChicagoT42OH008672 · OH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUCHANAN, SUSAN NATHALIE · 2005 to 2025
$32.7M
INVESTIGATIONS OF ENVIRONMENTAL EXPOSURES AND CANCERZ01CP010125 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI CANTOR, KENNETH · 1996 to 2008
$108k
Intramural NIH HHS Z01 CP010125Intramural NIH HHS Z01 CP01012522NIOSH CDC HHS T42 OH008672
6 · The paper itself

Abstract

backgroundParental occupational and childhood exposures to farm animals have been positively associated with childhood brain tumors, whereas associations with childhood leukemia are equivocal. The developing immune system may be influenced by allergen, virus, or other exposures from animal sources, which may contribute to childhood cancer incidence.

methodsIncident cancers (acute lymphoblastic leukemia [ALL], acute myeloid leukemia [AML], central nervous system [CNS], peripheral nervous system [PNS]) for children aged 0-4 diagnosed between 2003 and 2008 were obtained from nine National Cancer Institute Surveillance, Epidemiology and End Results (SEER) registries and were linked to U.S. Census of Agriculture data from 2002 and 2007 by county of diagnosis. Animal densities (animal units [AU]/km

resultsWe found positive associations between AML and broiler chicken densities (RR

conclusionsAlthough limited by the ecologic study design, some of our findings are novel and should be examined in epidemiological studies with individual level data.

Indexed as

LivestockPoultryAnimalsCentral Nervous System NeoplasmsChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornLeukemia, Myeloid, AcuteMaleNeoplasmsPeripheral Nervous System NeoplasmsPopulation DensityPrecursor Cell Lymphoblastic Leukemia-LymphomaAgricultural exposuresChildhood cancerEnvironmental epidemiologyFarm animalsLivestockPoultry

Identifiers

PMID28858758
PMCPMC5784771
OpenAlexW2755333989

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.