ArticleThe European journal of neuroscience2017
Effects of pair bonding on parental behavior and dopamine activity in the nucleus accumbens in male prairie voles.
Article in The European journal of neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 80 citations in OpenAlex.
- Parental styles are associated with eating disorder symptoms, anxiety, interpersonal difficulties, and nucleus accumbens response.Eating and weight disorders : EWD · 2024Article
- Re-wiring of the bonded brain: Gene expression among pair bonded female prairie voles changes as they transition to motherhood.Genes, brain, and behavior · 2024Article
- Psychostimulants and social behaviors.Frontiers in pharmacology · 2024Review
- Transcription and DNA methylation signatures of paternal behavior in hippocampal dentate gyrus of prairie voles.Scientific reports · 2023Article
- Transcriptomic analysis of paternal behaviors in prairie voles.BMC genomics · 2022Article
- Responses and functions of dopamine in nucleus accumbens core during social behaviors.Cell reports · 2022Article
- Systematic Input-Output Mapping Reveals Structural Plasticity of VTA Dopamine Neurons-Zona Incerta Loop Underlying the Social Buffering Effects in Learned Helplessness.Molecular neurobiology · 2022Article
- Differences in dopamine and opioid receptor ratios in the nucleus accumbens relate to physical contact and undirected song in pair-bonded zebra finches.Behavioral neuroscience · 2022Article
- The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022Review
- Birdsong and the Neural Regulation of Positive Emotion.Frontiers in psychology · 2022Review
- Raised without a father: monoparental care effects over development, sexual behavior, sexual reward, and pair bonding in prairie voles.Behavioural brain research · 2021Article
- The ventromedial hypothalamic circuitry and male alloparental behaviour in a socially monogamous rodent species.The European journal of neuroscience · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Male parental care is a vital behavior for the development as well as the physical and mental well-being of the young. However, little is known about the neurochemical regulation of male parental behavior, mainly due to the lack of appropriate animal models. In this study, we used the socially monogamous male prairie vole (Microtus ochrogaster) to investigate the effect of pair-bonding experience on paternal behavior and dopamine (DA) signaling in the nucleus accumbens (NAcc) in the brain. We compared sexually naïve males with males that were pair bonded with a female for two weeks. Our data showed that pair-bonded males displayed enhanced paternal behavior, particularly in pup licking/grooming, associated with increased DA type-1 receptor (D1R) protein expression in the NAcc, compared to sexually naïve males. Site-specific brain microdialysis revealed a significant, but transient, increase in DA release in the NAcc associated with pup exposure in both groups of the males. Further, pharmacological blockade of D1R in the NAcc decreased pup licking/grooming in the pair-bonded males. Together, our data demonstrate that pair-bonding experience with a female facilitated male parental behavior via NAcc D1R mediation in male prairie voles.
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