Evidence map›Paper›PMID 28858288›Full record

ArticleNature protocols2017

Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion.

Xiaoxia Liu, Alpay Burak Seven, Junjie Xu, Victoria Esser, Lijing Su, Cong Ma, Josep Rizo

Abstract read
In one paragraph

Article in Nature protocols, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
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  9. Article
  10. Review
  11. Synaptotagmin-1-, Munc18-1-, and Munc13-1-dependent liposome fusion with a few neuronal SNAREs.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Re-examining how Munc13-1 facilitates opening of syntaxin-1.Protein science : a publication of the Protein Society · 2020
    Article
  14. Structural and mechanistic insights into secretagogin-mediated exocytosis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoxia LiuDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Alpay Burak SevenDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Junjie XuDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Victoria EsserDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Lijing SuDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Cong MaKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Josep RizoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID http://orcid.org/0000-0003-1773-8311

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
STRUCTURE/FUNCTION OF SYNTAXIN 1R01NS037200 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 1998 to 2016
$6.5M
NINDS NIH HHS R01 NS037200NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

This protocol describes reconstitution assays to study how the neurotransmitter release machinery triggers Ca

Indexed as

Models, BiologicalColoring AgentsLipidsLiposomesMembrane FusionSNARE ProteinsSynaptic TransmissionSynaptic VesiclesVesicular Transport ProteinsColoring AgentsLipidsLiposomesSNARE ProteinsVesicular Transport Proteins

Identifiers

PMID28858288
PMCPMC6163043

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.