Evidence map›Paper›PMID 28858269›Full record

ReviewMaterials (Basel, Switzerland)2017

A Review of Recent Advances towards the Development of (Quantitative) Structure-Activity Relationships for Metallic Nanomaterials.

Guangchao Chen, Martina G Vijver, Yinlong Xiao, Willie J G M Peijnenburg

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guangchao ChenInstitute of Environmental Sciences, Leiden University, 2300 RA Leiden, The Netherlands. chen@cml.leidenuniv.nl.
Martina G VijverInstitute of Environmental Sciences, Leiden University, 2300 RA Leiden, The Netherlands. vijver@cml.leidenuniv.nl.
Yinlong XiaoInstitute of Environmental Sciences, Leiden University, 2300 RA Leiden, The Netherlands. xiao@cml.leidenuniv.nl.
Willie J G M PeijnenburgInstitute of Environmental Sciences, Leiden University, 2300 RA Leiden, The Netherlands. willie.peijnenburg@rivm.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gathering required information in a fast and inexpensive way is essential for assessing the risks of engineered nanomaterials (ENMs). The extension of conventional (quantitative) structure-activity relationships ((Q)SARs) approach to nanotoxicology, i.e., nano-(Q)SARs, is a possible solution. The preliminary attempts of correlating ENMs' characteristics to the biological effects elicited by ENMs highlighted the potential applicability of (Q)SARs in the nanotoxicity field. This review discusses the current knowledge on the development of nano-(Q)SARs for metallic ENMs, on the aspects of data sources, reported nano-(Q)SARs, and mechanistic interpretation. An outlook is given on the further development of this frontier. As concluded, the used experimental data mainly concern the uptake of ENMs by different cell lines and the toxicity of ENMs to cells lines and

Indexed as

cellular uptakemetallic nanomaterialsnano-(Q)SARsrisk assessmenttoxicity

Identifiers

PMID28858269
PMCPMC5615668

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.