Evidence map›Paper›PMID 28858244›Full record

ArticleMolecules (Basel, Switzerland)2017

Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake.

Xiao Chen, Jianbin Zhang, Lixia Yuan, Yifei Lay, Yin Kwan Wong, Teck Kwang Lim, Chye Sun Ong, Qingsong Lin, Jigang Wang, Zichun Hua

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  7. Diagnostics (Basel, Switzerland) · 2019
    Article
  8. Article
  9. Review
  10. Special Issue: Natural Products: Anticancer and Beyond.Molecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Xiao ChenThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China. pyb025@126.com.
Jianbin ZhangDepartment of Oncology, Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China. zhangjianbin@hmc.edu.cn.
Lixia YuanSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. cnylxtcm@163.com.
Yifei LayDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. layyifei@gmail.com.
Yin Kwan WongDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. e0146526@u.nus.edu.
Teck Kwang LimDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. dbslimtk@nus.edu.sg.
Chye Sun OngInstitute of Mental Health, Education Office, Singapore 539747, Singapore. Chye_Sun_ONG@imh.com.sg.
Qingsong LinDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. dbslinqs@nus.edu.sg.
Jigang WangDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. wangjigang@u.nus.edu.
Zichun HuaThe State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China. zchua@nju.edu.cn.
National University of Singapore · SGNanjing University · CNInstitute of Mental Health · SGSouthern Medical University · CNZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsCell Line, TumorCell ProliferationCell SurvivalDiterpenesDrug Screening Assays, AntitumorFatty Acidsfms-Like Tyrosine Kinase 3HumansIronProtein BiosynthesisSignal TransductionandrographolideAntineoplastic AgentsDiterpenesFatty AcidsFLT3 protein, humanfms-Like Tyrosine Kinase 3Ironandrographolidefatty acid synthesisFLT3 signalingintracellular iron poolMV4-11protein synthesisquantitative proteomics

Identifiers

PMID28858244
PMCPMC6151431
OpenAlexW2752659979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.