ArticleMedicine2017
Recurrent bacteremia and liver abscess caused by Clostridium difficile: A case report.
Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Extraintestinal Manifestations ofAntibiotics (Basel, Switzerland) · 2025Review
- Polymicrobial bacteraemia withBMJ case reports · 2022Article
- Partial hepatectomy for treatment of multiple liver abscess in a calf: a case report.BMC veterinary research · 2021Article
- Gastric cancer and adenomatous colorectal polyp concomitant with pyogenic liver abscess and bacteremia.Yeungnam University journal of medicine · 2020Article
- ExtraintestinalAntibiotics (Basel, Switzerland) · 2020Article
- Review
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Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleClostridium difficile bacteremia (CDB) and liver abscess is a quite rare presentation of C. difficile infection. PATIENTS CONCERNS: A 74-year-old male with primary biliary cirrhosis and hepatocellular carcinoma who underwent transarterial chemoembolization (TACE) developed a high fever on post-TACE day 14. Intravenous ceftriaxone and following meropenem were administered, however, his clinical response was poor. On post-TACE day 24, 2 sets of blood culture were taken due to elevation of C-reactive protein levels. DIAGNOSIS: CDB, caused by bacterial translocation.
interventionsIntravenous vancomycin and oral metronidazole were administered for two weeks. OUTCOMES: One month after recurrent CDB, the patient was re-admitted due to a liver abscess at the same site of TACE. C. difficile was isolated from the liver abscess and the patient received 6 weeks of oral metronidazole treatment. CDB and liver abscess have not recurred since completion of antibiotic treatment. LESSONS: The spore-forming ability of C. difficile may contributed to the recurrent CDB episodes and liver abscess formation in necrotic liver tissue following TACE, and long-term metronidazole therapy was considered to be effective to C. difficile liver abscess.
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