ArticleNucleic acids research1987
Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif.
Article in Nucleic acids research, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
58 citing papers in PubMed, 185 citations in OpenAlex.
- PABPC1 in Cancer: From a Translational Housekeeper to a Stress-Responsive Regulatory Hub.Cancer science · 2026Review
- PABPC1L depletion inhibits proliferation and migration via blockage of AKT pathway in human colorectal cancer cells.Oncology letters · 2019Article
- Potential roles of the poly(A)-binding proteins in translational regulation during spermatogenesis.The Journal of reproduction and development · 2018Review
- Identification and characterization of an hnRNP E1 translational silencing motif.Nucleic acids research · 2016Article
- Article
- PABPC1 exerts carcinogenesis in gastric carcinoma by targeting miR-34c.International journal of clinical and experimental pathology · 2015Article
- Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.PloS one · 2014Article
- PAB-1, a Caenorhabditis elegans poly(A)-binding protein, regulates mRNA metabolism in germline by interacting with CGH-1 and CAR-1.PloS one · 2013Article
- Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.Journal of virology · 2013Article
- Crystallization of oligonucleotides containing A-rich repeats suggests a structural contribution to the autoregulation mechanism of PABP translation.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012Article
- Functional characterization of three leishmania poly(a) binding protein homologues with distinct binding properties to RNA and protein partners.Eukaryotic cell · 2010Article
- Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.Nucleic acids research · 2007Article
- Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails.Molecular and cellular biology · 2006Article
- Interchromosomal segmental duplications of the pericentromeric region on the human Y chromosome.Genome research · 2005Article
- Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro.The EMBO journal · 2004Article
- RoXaN, a novel cellular protein containing TPR, LD, and zinc finger motifs, forms a ternary complex with eukaryotic initiation factor 4G and rotavirus NSP3.Journal of virology · 2004Article
- Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease.Journal of virology · 2002Article
- Vasopressin mRNA localization in nerve cells: characterization of cis-acting elements and trans-acting factors.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Human testis expresses a specific poly(A)-binding protein.Nucleic acids research · 2001Article
- Glucocorticoid-induced DNA demethylation and gene memory during development.The EMBO journal · 2001Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have isolated a full length cDNA (cDNA) coding for the human poly(A) binding protein. The cDNA derived 73 kd basic translation product has the same Mr, isoelectric point and peptidic map as the poly(A) binding protein. DNA sequence analysis reveals a 70,244 dalton protein. The N terminal part, highly homologous to the yeast poly(A) binding protein, is sufficient for poly(A) binding activity. This domain consists of a four-fold repeated unit of approximately 80 amino acids present in other nucleic acid binding proteins. In the C terminal part there is, as in the yeast protein, a sequence of approximately 150 amino acids, rich in proline, alanine and glutamine which together account for 48% of the residues. A 2,9 kb mRNA corresponding to this cDNA has been detected in several vertebrate cell types and in Drosophila melanogaster at every developmental stage including oogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.