Evidence map›Paper›PMID 28858036›Full record

ArticleNeuroreport2017

Altered regional homogeneity in patients with late monocular blindness: a resting-state functional MRI study.

Xin Huang, Cheng-Long Ye, Yu-Lin Zhong, Lei Ye, Qi-Chen Yang, Hai-Jun Li, Nan Jiang, De-Chang Peng, Yi Shao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroreport, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

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  18. Disrupted resting-state spontaneous neural activity in stable COPD.International journal of chronic obstructive pulmonary disease
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xin HuangDepartments of aOphthalmology bRadiology, The First Affiliated Hospital of Nanchang University, Nanchang cDepartment of Ophthalmology, The First People's Hospital of Jiujiang City, Jiujiang, Jiangxi Province dEye Institute of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen, Fujian Province, China.
Cheng-Long Ye
Yu-Lin Zhong
Lei Ye
Qi-Chen Yang
Hai-Jun Li
Nan Jiang
De-Chang Peng
Yi Shao
Nanchang University · CNOphthalmology Associates (United States) · USFirst Affiliated Hospital of Nanchang University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many previous studies have demonstrated that the blindness patients have has functional and anatomical abnormalities in the visual and other vision-related cortex. However, changes in the brain function in late monocular blindness (MB) at rest are largely unknown. In this study, we investigated the underlying regional homogeneity (ReHo) of brain-activity abnormalities in patients with late MB and their relationship with clinical features. A total of 32 patients with MB (25 male and seven female) and 32 healthy controls (HCs) (25 male and seven female) closely matched in age, sex, and education underwent resting-state functional MRI scans. The ReHo method was used to assess local features of spontaneous brain activities. Patients with MB were distinguishable from HCs using the receiver operating characteristic curve. The relationship between the mean ReHo in brain regions and the behavioral performance was calculated using correlation analysis. Compared with HCs, patients with MB showed significantly decreased ReHo values in the right rectal gyrus, right cuneus, right anterior cingulate, and right lateral occipital cortex and increased ReHo values in the right inferior temporal gyrus, right frontal middle orbital, left posterior cingulate/precuneus, and left middle frontal gyrus. However, there was no significant relationship between the different mean ReHo values in the brain regions and the clinical features. Late MB involves abnormalities of the visual cortex and other vision-related brain regions, which may reflect brain dysfunction in these regions.

Indexed as

AdultBlindnessCase-Control StudiesCerebral CortexFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMiddle Aged

Identifiers

PMID28858036
PMCPMC5916480
OpenAlexW2751274818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.