Evidence map›Paper›PMID 28857047›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case-control study, Spain, 2013/14 and 2014/15.

Angela Domínguez, Núria Soldevila, Diana Toledo, Pere Godoy, Elena Espejo, Maria Amelia Fernandez, José María Mayoral, Jesús Castilla, Mikel Egurrola, Sonia Tamames and 3 more

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. [Economic and Health impact of influenza vaccination with adjuvant MF59 in population over 64 years in Spain].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Angela DomínguezCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Núria SoldevilaDepartament de Medicina, Universitat de Barcelona, Barcelona, Spain.
Diana ToledoDepartament de Medicina, Universitat de Barcelona, Barcelona, Spain.
Pere GodoyInstitut de Recerca Biomèdica de Lleida, Universitat de Lleida, Lleida, Spain.
Elena EspejoHospital de Terrassa, Terrassa, Spain.
Maria Amelia FernandezComplejo Hospitalario Universitario de Granada, Granada, Spain.
José María MayoralServicio de Vigilancia de Andalucía, Sevilla, Spain.
Jesús CastillaCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Mikel EgurrolaHospital de Galdakao, Usansolo, Spain.
Sonia TamamesDirección General de Salud Pública, Investigación, Desarrollo e Innovación, Junta de Castilla y León, León, Spain.
Jenaro AstrayConsejería de Sanidad, Madrid, Spain.
María Morales-Suárez-VarelaCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
The Working Group Of The Project Pi/The members of the Working Group are listed at the end of the article.
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESComplejo Hospitalario Universitario de Granada · ESComunidad de Madrid · ESHospital de Galdakao · ESHospital Terrassa · ESInstituto de Salud Pública de Navarra · ESJunta de Castilla y León · ESUniversitat de Lleida · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22-47). VE was 51% (95% CI: 15-71) in patients without high-risk medical conditions and 30% (95% CI: 14-44) in patients with them. VE was 39% (95% CI: 20-53) in patients aged 65-79 years and 34% (95% CI: 11-51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.

Indexed as

Vaccine PotencyAgedAged, 80 and overCase-Control StudiesFemaleHospitalizationHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesLogistic ModelsMaleOutcome Assessment, Health CarePopulation SurveillanceSeasonsInfluenza Vaccineseffectivenesselderlyhospitalised cases, hospitalised controlsinfluenzamatched case–controlvaccination

Identifiers

PMID28857047
PMCPMC5753443
OpenAlexW2751822928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.