Evidence map›Paper›PMID 28856849›Full record

ReviewStem cells (Dayton, Ohio)2017

Concise Review: Mechanisms of Quiescent Hair Follicle Stem Cell Regulation.

Rui Yi

Open access · greenAbstract readReview
In one paragraph

Review in Stem cells (Dayton, Ohio), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Biomedicines · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Durable CD4Trends in immunology · 2024
    Review
  17. Review
  18. The Roles of Exosomes in Regulating Hair Follicle Growth.Clinical, cosmetic and investigational dermatology · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rui YiDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA.ORCID 0000-0002-6934-7091
University of Colorado Boulder · US

Funding

MicroRNA-mediated Regulation in Mammalian SkinR01AR059697 · NIAMS · UNIVERSITY OF COLORADO · PI YI, RUI · 2010 to 2020
$3.9M
Genetic Analysis of MicroRNA Functions in Skin Stem Cells In VivoR01AR066703 · NIAMS · UNIVERSITY OF COLORADO · PI YI, RUI · 2014 to 2024
$3.9M
Transcriptional regulation of skin stem cells and their nicheR01AR071435 · NIAMS · UNIVERSITY OF COLORADO · PI Rui Yi · 2017 to 2026
$3.8M
NIAMS NIH HHS R01 AR059697NIAMS NIH HHS R01 AR066703NIAMS NIH HHS R01 AR071435
6 · The paper itself

Abstract

Maintaining a pool of adult stem cells is essential for tissue homeostasis and wound repair. In mammalian tissues, notably hair follicles, blood, and muscle, stem cells acquire quiescence and infrequently divide for self-renewal. Mechanistic understanding of stem cell quiescence is critical for applying these multipotent cells in regenerative medicine and interrogating their roles in human diseases such as cancer. Quiescent and dividing epithelial stem cells located in hair follicle are conspicuously organized in a spatiotemporally specific manner, allowing them to be studied at a considerable depth. Recent advancements in mouse genetics, genomics, and imaging have revealed unprecedented insights into establishment, maintenance, and regulation of quiescent hair follicle stem cells. This concise review summarizes the progress with a focus on mechanisms mediated by signaling pathways and transcription factors and discusses their implications in the understanding of stem cell biology. Stem Cells 2017;35:2323-2330.

Indexed as

AnimalsCell DifferentiationHair FollicleHumansSignal TransductionStem CellsAdult stem cellsCell signalingEpidermisSelf-renewalTranscriptional regulation

Identifiers

PMID28856849
PMCPMC5743437
OpenAlexW2750921796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.