Evidence map›Paper›PMID 28856834›Full record

ReviewJournal of clinical hypertension (Greenwich, Conn.)2017

Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence.

Keith C Ferdinand, Kapil Yadav, Samar A Nasser, Helene D Clayton-Jeter, John Lewin, Dennis R Cryer, Fortunato Fred Senatore

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06155240 (Yoga for a Healthy Heart Study), which is not on this map. Cited by 101 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06155240 nacompletednot on this mapstarted 2024, after this paper: background citation

Yoga for a Healthy Heart Study: Addressing Stress Management and Functional Cognition as Barriers to Both Medication Management and Blood Pressure Regulation for African American Patients With Hypertension

TypeinterventionalSponsorThe Cleveland ClinicRan2024 to 2024Enrolled8ConditionsHypertensionArmsTherapeutic yoga
3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 3 syntheses or guidelines pooled it, 192 citations in OpenAlex.

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  3. Ambulatory Medication Safety in Primary Care: A Systematic Review.Journal of the American Board of Family Medicine : JABFM
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  16. Health Disparity Indices in the Assessment of Adolescent Idiopathic Scoliosis: Are All Indices Similar?Journal of the Pediatric Orthopaedic Society of North America · 2025
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Keith C FerdinandTulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, LA, USA.ORCID http://orcid.org/0000-0003-3338-4410
Kapil YadavTulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, LA, USA.
Samar A NasserDepartment of Clinical Research & Leadership, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
Helene D Clayton-JeterCardiovascular and Endocrine Liaison Program, Office of the Commissioner/External Affairs/Health & Constituent Affairs, Food and Drug Administration, Silver Springs, MD, USA.
John LewinLewin and Associates LLC, National Coalition on Health Care, Washington, DC, USA.
Dennis R CryerCryerHealth, Washington, DC, USA.
Fortunato Fred SenatoreCenter for Drug Evaluation Research, Food and Drug Administration, Silver Springs, MD, USA.
Tulane University · USAcademyHealth · USCenter for Drug Evaluation and Research · USGeorge Washington University · USNational Business Group on Health · USUnited States Food and Drug Administration · US

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

Blacks are two to three times as likely as whites to die of preventable heart disease and stroke. Declines in mortality from heart disease have not eliminated racial disparities. Control and effective treatment of hypertension, a leading cause of cardiovascular disease, among blacks is less than in whites and remains a challenge. One of the driving forces behind this racial/ethnic disparity is medication nonadherence whose cause is embedded in social determinants. Eight practical approaches to addressing medication adherence with the potential to attenuate disparities were identified and include: (1) patient engagement strategies, (2) consumer-directed health care, (3) patient portals, (4) smart apps and text messages, (5) digital pillboxes, (6) pharmacist-led engagement, (7) cardiac rehabilitation, and (8) cognitive-based behavior. However, while data suggest that these strategies may improve medication adherence, the effect on ameliorating racial/ethnic disparities is not certain. This review describes the relationship between disparities and medication adherence, which likely plays a role in persistent disparities in cardiovascular morbidity and mortality.

Indexed as

Antihypertensive AgentsAwarenessBlack or African AmericanCardiovascular DiseasesDrug MonitoringFemaleHealthcare DisparitiesHispanic or LatinoHumansHypertensionMaleMedication AdherenceRetrospective StudiesSocial ClassUnited StatesWhite PeopleAntihypertensive AgentsAdherenceblackscardiovascular diseaseFood and Drug Administrationhealth disparitieshypertensionrace/ethnicity

Identifiers

PMID28856834
PMCPMC5638710
OpenAlexW2753828872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.