Evidence map›Paper›PMID 28856770›Full record

ArticleEnvironmental and molecular mutagenesis2017

Genotoxic effects of high dose rate X-ray and low dose rate gamma radiation in Apc

Anne Graupner, Dag M Eide, Dag A Brede, Michele Ellender, Elisabeth Lindbo Hansen, Deborah H Oughton, Simon D Bouffler, Gunnar Brunborg, Ann Karin Olsen

Open access · hybridAbstract read
In one paragraph

Article in Environmental and molecular mutagenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Anne GraupnerDepartment of Molecular Biology, Norwegian Institute of Public Health, Oslo, 0403, Norway.
Dag M EideCentre for Environmental Radioactivity (CoE CERAD), Ås 1432, Norway.
Dag A BredeCentre for Environmental Radioactivity (CoE CERAD), Ås 1432, Norway.
Michele EllenderRadiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, England.
Elisabeth Lindbo HansenCentre for Environmental Radioactivity (CoE CERAD), Ås 1432, Norway.
Deborah H OughtonCentre for Environmental Radioactivity (CoE CERAD), Ås 1432, Norway.
Simon D BoufflerRadiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, England.
Gunnar BrunborgDepartment of Molecular Biology, Norwegian Institute of Public Health, Oslo, 0403, Norway.
Ann Karin OlsenDepartment of Molecular Biology, Norwegian Institute of Public Health, Oslo, 0403, Norway.
Norwegian Institute of Public Health · NONorwegian University of Life Sciences · NOPublic Health England · GBNorwegian Radiation and Nuclear Safety Authority · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Risk estimates for radiation-induced cancer in humans are based on epidemiological data largely drawn from the Japanese atomic bomb survivor studies, which received an acute high dose rate (HDR) ionising radiation. Limited knowledge exists about the effects of chronic low dose rate (LDR) exposure, particularly with respect to the application of the dose and dose rate effectiveness factor. As part of a study to investigate the development of colon cancer following chronic LDR vs. acute HDR radiation, this study presents the results of genotoxic effects in blood of exposed mice. CBAB6 F1 Apc

Indexed as

Adenomatous Polyposis Coli ProteinAnimalsCell SurvivalChromosome AberrationsDNA DamageDose-Response Relationship, RadiationGamma RaysHumansMiceMicronucleus TestsMutationNeoplasms, Radiation-InducedX-RaysAdenomatous Polyposis Coli Proteinblood cellschronic and acute irradiationDNA lesionsmicronucleimutation

Identifiers

PMID28856770
PMCPMC5656900
OpenAlexW2752418824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.