Evidence map›Paper›PMID 28856763›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2018

The fly eye: Through the looking glass.

Justin P Kumar

Open access · bronzeAbstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. TheFrontiers in neuroscience · 2025
    Article
  3. Article
  4. Flynotyper 2.0: An updated tool for rapid quantitative assessment ofbioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Application of Fluorescent Proteins for Functional Dissection of theInternational journal of molecular sciences · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Justin P KumarDepartment of Biology, Indiana University, Bloomington, Indiana.ORCID 0000-0001-9991-7932
Indiana University Bloomington · US

Funding

Repression of Non-Ocular Fates by the SIX and EYA Genes During Specification and Patterning of the RetinaR01EY014863 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI KUMAR, JUSTIN P · 2003 to 2017
$4.3M
NEI NIH HHS R01 EY014863
6 · The paper itself

Abstract

The developing eye-antennal disc of Drosophila melanogaster has been studied for more than a century, and it has been used as a model system to study diverse processes, such as tissue specification, organ growth, programmed cell death, compartment boundaries, pattern formation, cell fate specification, and planar cell polarity. The findings that have come out of these studies have informed our understanding of basic developmental processes as well as human disease. For example, the isolation of a white-eyed fly ultimately led to a greater appreciation of the role that sex chromosomes play in development, sex determination, and sex linked genetic disorders. Similarly, the discovery of the Sevenless receptor tyrosine kinase pathway not only revealed how the fate of the R7 photoreceptor is selected but it also helped our understanding of how disruptions in similar biochemical pathways result in tumorigenesis and cancer onset. In this article, I will discuss some underappreciated areas of fly eye development that are fertile for investigation and are ripe for producing exciting new breakthroughs. The topics covered here include organ shape, growth control, inductive signaling, and right-left symmetry. Developmental Dynamics 247:111-123, 2018. © 2017 Wiley Periodicals, Inc.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsCell DifferentiationDrosophila melanogasterDrosophila ProteinsPhotoreceptor Cells, InvertebrateReceptor Protein-Tyrosine KinasesRetinaSignal TransductionDrosophila ProteinsReceptor Protein-Tyrosine KinasesDrosophilaeyeeye-antennal imaginal discperipodial epitheliumretinashapesizesymmetry

Identifiers

PMID28856763
PMCPMC5746045
OpenAlexW2752174001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.