Evidence map›Paper›PMID 28856120›Full record

ArticleThe journal of prevention of Alzheimer's disease2017

From Brain Disease to Brain Health: Primary Prevention of Alzheimer's Disease and Related Disorders in a Health System Using an Electronic Medical Record-Based Approach.

A M Fosnacht, S Patel, C Yucus, A Pham, E Rasmussen, R Frigerio, S Walters, D Maraganore

Open access · bronzeAbstract read
In one paragraph

Article in The journal of prevention of Alzheimer's disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Primary prevention recommendations to reduce the risk of cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Article
  4. Article
  5. Classification of Transgenic Mice by Retinal Imaging Using SVMS.Computational intelligence and neuroscience · 2022
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A M FosnachtNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
S PatelNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
C YucusNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
A PhamNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
E RasmussenNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
R FrigerioNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
S WaltersResearch Institute, NorthShore University HealthSystem, Evanston, IL, USA.
D MaraganoreNorthShore Neurological Institute, NorthShore University HealthSystem, Evanston, IL, USA.
NorthShore University HealthSystem · US

Funding

Quality Improvement and Practice Based Research in Neurology Using the EMRR01HS024057 · AHRQ · UNIVERSITY OF FLORIDA · PI MARAGANORE, DEMETRIUS MICHAEL · 2015 to 2019
$1.1M
AHRQ HHS R01 HS024057
6 · The paper itself

Abstract

backgroundAlzheimer's disease and aging brain disorders are progressive, often fatal neurodegenerative diseases. Successful aging, modern lifestyles and behaviors have combined to result in an expected epidemic. Risks for these diseases include genetic, medical, and lifestyle factors; over 20 modifiable risks have been reported.

objectivesWe aim to primarily prevent Alzheimer's disease and related disorders through electronic medical record (EMR)-based screening, risk assessments, interventions, and surveillance.

designWe identified modifiable risks; developed human, systems and infrastructural resources; developed interventions; and targeted at-risk groups for the intervention.

settingA Community Based Health System.

participantsIn year one (June 2015 to May 2016), 133 at-risk patients received brain health services with the goal of delaying or preventing Alzheimer's disease and related disorders. MEASUREMENTS: We created mechanisms to identify patients at high risk of neurodegenerative disease; EMR-based structured clinical documentation support tools to evaluate risk factors and history; evidence-based interventions to modify risk; and the capacity for annual surveillance, pragmatic trials, and practice-based and genomic research using the EMR.

resultsThis paper describes our Center for Brain Health, our EMR tools, and our first year of healthy but at-risk patients.

conclusionWe are translating research into primary prevention of Alzheimer's disease and related disorders in our health system and aim to shift the paradigm in Neurology from brain disease to brain health.

Indexed as

brain healthelectronic medical recordNeurodegenerationprimary preventionrisk assessmentssurveillance

Identifiers

PMID28856120
PMCPMC5573186
OpenAlexW2900883636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.