Evidence map›Paper›PMID 28856051›Full record

ArticleBiomedical optics express2017

Line scanning, stage scanning confocal microscope (LSSSCM).

Daniel S Gareau, James G Krueger, Jason E Hawkes, Samantha R Lish, Michael P Dietz, Alba Guembe Mülberger, Euphemia W Mu, Mary L Stevenson, Jesse M Lewin, Shane A Meehan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Current Landscape of Advanced Imaging Tools for Pathology Diagnostics.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Fluorescence imaging with tailored light.Nanophotonics (Berlin, Germany) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Daniel S GareauInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
James G KruegerInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
Jason E HawkesInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
Samantha R LishInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
Michael P DietzInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
Alba Guembe MülbergerInvestigative Dermatology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.
Euphemia W MuRonald O. Pearleman Department of Dermatology, New York University, 240 E. 38th St., New York, NY 10016, USA.
Mary L StevensonRonald O. Pearleman Department of Dermatology, New York University, 240 E. 38th St., New York, NY 10016, USA.
Jesse M LewinDepartment of Dermatology, Columbia University Medical Center, 161 Fort Washington Avenue, 12th Floor, New York, NY 10032, USA.
Shane A MeehanRonald O. Pearleman Department of Dermatology, New York University, 240 E. 38th St., New York, NY 10016, USA.
John A CarucciRonald O. Pearleman Department of Dermatology, New York University, 240 E. 38th St., New York, NY 10016, USA.
Columbia University Irving Medical Center · US

Funding

Clinical translation of video assisted micrographic surgery for staged cancer removalR01CA193390 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARUCCI, JOHN A · 2015 to 2017
$898k
NCI NIH HHS R01 CA193390
6 · The paper itself

Abstract

For rapid pathological assessment of large surgical tissue excisions with cellular resolution, we present a line scanning, stage scanning confocal microscope (LSSSCM). LSSSCM uses no scanning mirrors. Laser light is focused with a single cylindrical lens to a line of diffraction-limited width directly into the (Z) sample focal plane, which is parallel to and near the flattened specimen surface. Semi-confocal optical sections are derived from the linear array distribution (Y) and a single mechanical drive that moves the sample parallel to the focal plane and perpendicular to the focused line (X). LSSSCM demonstrates cellular resolution in the conditions of high nuclear density within micronodular basal cell carcinoma.

Indexed as

(110.0180) Microscopy(170.1790) Confocal microscopy(170.1870) Dermatology(170.5810) Scanning microscopy(170.7050) Turbid media

Identifiers

PMID28856051
PMCPMC5560842
OpenAlexW2737477046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.