Evidence map›Paper›PMID 28856039›Full record

ArticleBiomedical optics express2017

Classification of biological micro-objects using optical coherence tomography: in silico study.

Paweł Ossowski, Maciej Wojtkowski, Peter Rt Munro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paweł OssowskiInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University Grudziadzka 5, 87-100 Torun, Poland.
Maciej WojtkowskiInstitute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University Grudziadzka 5, 87-100 Torun, Poland.
Peter Rt MunroDepartment of Medical Physics and Biomedical Engineering, University College London, Malet Place, Gower Street, London WC1E 6BT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on the development of a technique for differentiating between biological micro-objects using a rigorous, full-wave model of OCT image formation. We model an existing experimental prototype which uses OCT to interrogate a microfluidic chip containing the blood cells. A full-wave model is required since the technique uses light back-scattered by a scattering substrate, rather than by the cells directly. The light back-scattered by the substrate is perturbed upon propagation through the cells, which flow between the substrate and imaging system's objective lens. We present the key elements of the 3D, Maxwell equation-based computational model, the key findings of the computational study and a comparison with experimental results.

Indexed as

(050.1755) Computational electromagnetic methods(110.4500) Optical coherence tomography(170.1470) Blood or tissue constituent monitoring(170.3660) Light propagation in tissues(170.3880) Medical and biological imaging

Identifiers

PMID28856039
PMCPMC5560829

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.