Evidence map›Paper›PMID 28856036›Full record

ArticleBiomedical optics express2017

Optical coherence tomography angiography of retinal vascular occlusions produced by imaging-guided laser photocoagulation.

Brian T Soetikno, Xiao Shu, Qi Liu, Wenzhong Liu, Siyu Chen, Lisa Beckmann, Amani A Fawzi, Hao F Zhang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Visible-light optical coherence tomography: a review.Journal of biomedical optics · 2017
    Review
  15. Advances in multimodal imaging in ophthalmology.Therapeutic advances in ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Brian T SoetiknoDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Xiao ShuDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Qi LiuDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Wenzhong LiuDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Siyu ChenDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Lisa BeckmannDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Amani A FawziDepartment of Ophthalmology, Northwestern University, Chicago, IL, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Northwestern University · US

Funding

Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
Functional Retinal Imaging to Monitor Pharmaco-Therapies in Diabetic RetinopathyDP3DK108248 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FAWZI, AMANI A, ZHANG, HAO F · 2015 to 2015
$1.9M
Oxygen delivery and metabolism in diabetic retinopathy using visible-light optical coherence tomographyF30EY026472 · NEI · NORTHWESTERN UNIVERSITY · PI SOETIKNO, BRIAN THEODORE · 2016 to 2020
$193k
NEI NIH HHS F30 EY026472NEI NIH HHS R01 EY026078NIDDK NIH HHS DP3 DK108248
6 · The paper itself

Abstract

Retinal vascular occlusive diseases represent a major form of vision loss worldwide. Rodent models of these diseases have traditionally relied upon a slit-lamp biomicroscope to help visualize the fundus and subsequently aid delivery of high-power laser shots to a target vessel. Here we describe a multimodal imaging system that can produce, image, and monitor retinal vascular occlusions in rodents. The system combines a spectral-domain optical coherence tomography system for cross-sectional structural imaging and three-dimensional angiography, and a fluorescence scanning laser ophthalmoscope for Rose Bengal monitoring and high-power laser delivery to a target vessel. This multimodal system facilitates the precise production of occlusions in the branched retinal veins, central retinal vein, and branched retinal arteries. Additionally, changes in the retinal morphology and retinal vasculature can be longitudinally documented. With our device, retinal vascular occlusions can be easily and consistently created, which paves the way for futures studies on their pathophysiology and therapeutic targets.

Indexed as

(170.0110) Imaging systems(170.2520) Fluorescence microscopy(170.4470) Ophthalmology(170.4500) Optical coherence tomography

Identifiers

PMID28856036
PMCPMC5560826
OpenAlexW2726790408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.